Search TCDB: (?)
TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


3.A.1.15.5
Zinc (Zn2+) porter of E. coli, ZnuABC.  Required for Zn2+ homeostasis and virulence in the close E. coli relative, Salmonella enterica (Ammendola et al., 2007).

Accession Number:P0A9X1
Protein Name:ZnuC aka B1858
Length:251
Molecular Weight:27867.00
Species:Escherichia coli [83333]
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Peripheral membrane protein2
Substrate zinc(2+)

Cross database links:

DIP: DIP-48234N
RefSeq: AP_002478.1    NP_416372.1   
Entrez Gene ID: 946374   
Pfam: PF00005   
BioCyc: EcoCyc:ZNUC-MONOMER    ECOL168927:B1858-MONOMER   
KEGG: ecj:JW1847    eco:b1858   

Gene Ontology

GO:0005886 C:plasma membrane
GO:0005524 F:ATP binding
GO:0016887 F:ATPase activity
GO:0015633 F:zinc transporting ATPase activity
GO:0006829 P:zinc ion transport

References (5)

[1] “A 460-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 40.1-50.0 min region on the linkage map.”  Itoh T.et.al.   9097040
[2] “The complete genome sequence of Escherichia coli K-12.”  Blattner F.R.et.al.   9278503
[3] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.”  Hayashi K.et.al.   16738553
[4] “The ZnuABC high-affinity zinc uptake system and its regulator Zur in Escherichia coli.”  Patzer S.I.et.al.   9680209
[5] “Transcriptional response of Escherichia coli to external zinc.”  Yamamoto K.et.al.   16159766

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence 
1:	MTSLVSLENV SVSFGQRRVL SDVSLELKPG KILTLLGPNG AGKSTLVRVV LGLVTPDEGV 
61:	IKRNGKLRIG YVPQKLYLDT TLPLTVNRFL RLRPGTHKED ILPALKRVQA GHLINAPMQK 
121:	LSGGETQRVL LARALLNRPQ LLVLDEPTQG VDVNGQVALY DLIDQLRREL DCGVLMVSHD 
181:	LHLVMAKTDE VLCLNHHICC SGTPEVVSLH PEFISMFGPR GAEQLGIYRH HHNHRHDLQG 
241:	RIVLRRGNDR S