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8.A.254.1.1 The MrdAB (PBP2/RodA) complex for peptidoglycan synthesis and placement between the inner and outer membranes of Gram-negative bacteria (Nygaard et al. 2023). MdrA/PBP2 of 633 aas has 1 N-terminal TMS while MdrB/RodA of 370 aas has 9 TMSs in a 3 + 3 + 3 TMS arrangement.
Accession Number:	P0AD65
Protein Name:	Peptidoglycan D,D-transpeptidase MrdA
Length:	633
Molecular Weight:	70857.00
Species:	Escherichia coli (strain K12) [83333]
Number of TMSs:	1
Location¹ / Topology² / Orientation³:	Cell inner membrane¹ / Single-pass membrane protein²
Substrate

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MKLQNSFRDY TAESALFVRR ALVAFLGILL LTGVLIANLY NLQIVRFTDY QTRSNENRIK 
61:	LVPIAPSRGI IYDRNGIPLA LNRTIYQIEM MPEKVDNVQQ TLDALRSVVD LTDDDIAAFR 
121:	KERARSHRFT SIPVKTNLTE VQVARFAVNQ YRFPGVEVKG YKRRYYPYGS ALTHVIGYVS 
181:	KINDKDVERL NNDGKLANYA ATHDIGKLGI ERYYEDVLHG QTGYEEVEVN NRGRVIRQLK 
241:	EVPPQAGHDI YLTLDLKLQQ YIETLLAGSR AAVVVTDPRT GGVLALVSTP SYDPNLFVDG 
301:	ISSKDYSALL NDPNTPLVNR ATQGVYPPAS TVKPYVAVSA LSAGVITRNT TLFDPGWWQL 
361:	PGSEKRYRDW KKWGHGRLNV TRSLEESADT FFYQVAYDMG IDRLSEWMGK FGYGHYTGID 
421:	LAEERSGNMP TREWKQKRFK KPWYQGDTIP VGIGQGYWTA TPIQMSKALM ILINDGIVKV 
481:	PHLLMSTAED GKQVPWVQPH EPPVGDIHSG YWELAKDGMY GVANRPNGTA HKYFASAPYK 
541:	IAAKSGTAQV FGLKANETYN AHKIAERLRD HKLMTAFAPY NNPQVAVAMI LENGGAGPAV 
601:	GTLMRQILDH IMLGDNNTDL PAENPAVAAA EDH

8.A.254.1.1
The MrdAB (PBP2/RodA) complex for peptidoglycan synthesis and placement between the inner and outer membranes of Gram-negative bacteria (Nygaard et al. 2023). MdrA/PBP2 of 633 aas has 1 N-terminal TMS while MdrB/RodA of 370 aas has 9 TMSs in a 3 + 3 + 3 TMS arrangement.

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8.A.254.1.1The MrdAB (PBP2/RodA) complex for peptidoglycan synthesis and placement between the inner and outer membranes of Gram-negative bacteria (Nygaard et al. 2023). MdrA/PBP2 of 633 aas has 1 N-terminal TMS while MdrB/RodA of 370 aas has 9 TMSs in a 3 + 3 + 3 TMS arrangement.

Cross database links:

External Searches:

Analyze:

8.A.254.1.1
The MrdAB (PBP2/RodA) complex for peptidoglycan synthesis and placement between the inner and outer membranes of Gram-negative bacteria (Nygaard et al. 2023). MdrA/PBP2 of 633 aas has 1 N-terminal TMS while MdrB/RodA of 370 aas has 9 TMSs in a 3 + 3 + 3 TMS arrangement.