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3.A.1.6.1
Sulfate/thiosulfate porter

Accession Number:P0AEB0
Protein Name:Sulfate transport system permease protein CysW aka B2423
Length:291
Molecular Weight:32538.00
Species:Escherichia coli [83333]
Number of TMSs:6
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate sulfate, thiosulfate(2-)

Cross database links:

RefSeq: AP_003017.1    YP_026168.2   
Entrez Gene ID: 2847743   
Pfam: PF00528   
BioCyc: EcoCyc:CYSW-MONOMER    ECOL168927:B2423-MONOMER   
KEGG: ecj:JW2416    eco:b2423   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0015116 F:sulfate transmembrane transporter activity
GO:0015563 F:uptake transmembrane transporter activity
GO:0008272 P:sulfate transport

References (5)

[1] “Sulfate and thiosulfate transport in Escherichia coli K-12: nucleotide sequence and expression of the cysTWAM gene cluster.”  Sirko A.et.al.   2188958
[2] “Construction of a contiguous 874-kb sequence of the Escherichia coli-K12 genome corresponding to 50.0-68.8 min on the linkage map and analysis of its sequence features.”  Yamamoto Y.et.al.   9205837
[3] “The complete genome sequence of Escherichia coli K-12.”  Blattner F.R.et.al.   9278503
[4] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.”  Hayashi K.et.al.   16738553
[5] “Global topology analysis of the Escherichia coli inner membrane proteome.”  Daley D.O.et.al.   15919996

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence 
1:	MAEVTQLKRY DARPINWGKW FLIGIGMLVS AFILLVPMIY IFVQAFSKGL MPVLQNLADP 
61:	DMLHAIWLTV MIALIAVPVN LVFGILLAWL VTRFNFPGRQ LLLTLLDIPF AVSPVVAGLV 
121:	YLLFYGSNGP LGGWLDEHNL QIMFSWPGMV LVTIFVTCPF VVRELVPVML SQGSQEDEAA 
181:	ILLGASGWQM FRRVTLPNIR WALLYGVVLT NARAIGEFGA VSVVSGSIRG ETLSLPLQIE 
241:	LLEQDYNTVG SFTAAALLTL MAIITLFLKS MLQWRLENQE KRAQQEEHHE H