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3.A.1.8.1
Molybdate porter consisting of three proteins.  Molybdate, after transport into cells by the ModABC proteins, is metabolized by the products of the mol gene(s) (Maupin-Furlow et al. 1995). The repressor of the mod operon is ModE (Grunden et al. 1996).

Accession Number:P0AF01
Protein Name:Molybdenum transport system permease protein ModB aka CHLJ aka B0764
Length:229
Molecular Weight:24939.00
Species:Escherichia coli [83333]
Number of TMSs:5
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate Molybdate

Cross database links:

Genevestigator: P0AF01
EchoBASE: EB0002
EcoGene: EG10002
eggNOG: COG4149
HEGENOM: HBG685300
RefSeq: AP_001395.1    NP_415285.1   
Entrez Gene ID: 945361   
Pfam: PF00528   
BioCyc: EcoCyc:MODB-MONOMER    ECOL168927:B0764-MONOMER   
KEGG: ecj:JW0747    eco:b0764   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0015098 F:molybdate ion transmembrane transporter act...
GO:0005515 F:protein binding
GO:0015689 P:molybdate ion transport

References (7)

[1] “Genetic analysis of the modABCD (molybdate transport) operon of Escherichia coli.”  Maupin-Furlow J.A.et.al.   7665460
[2] “Molecular analysis of the molybdate uptake operon, modABCD, of Escherichia coli and modR, a regulatory gene.”  Walkenhorst H.M.et.al.   8564363
[3] “A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 12.7-28.0 min region on the linkage map.”  Oshima T.et.al.   8905232
[4] “The complete genome sequence of Escherichia coli K-12.”  Blattner F.R.et.al.   9278503
[5] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.”  Hayashi K.et.al.   16738553
[6] “Cloning and nucleotide sequence of the chlD locus.”  Johann S.et.al.   3553151
[7] “Global topology analysis of the Escherichia coli inner membrane proteome.”  Daley D.O.et.al.   15919996

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence
1:	MILTDPEWQA VLLSLKVSSL AVLFSLPFGI FFAWLLVRCT FPGKALLDSV LHLPLVLPPV 
61:	VVGYLLLVSM GRRGFIGERL YDWFGITFAF SWRGAVLAAA VMSFPLMVRA IRLALEGVDV 
121:	KLEQAARTLG AGRWRVFFTI TLPLTLPGII VGTVLAFARS LGEFGATITF VSNIPGETRT 
181:	IPSAMYTLIQ TPGGESGAAR LCIISIALAM ISLLISEWLA RISRERAGR