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3.D.1.1.1 NADH dehydrogenase I, NuoA-N. NuoL probably comprises part of the proton pathway (Nakamaru-Ogiso et al. 2010). NuoL (ND5), NuoM (ND4) and NuoN (ND2) are all homologous to proton:sodium antiporters and may all play reoles in pumping protons using a similar mechanism (Sato et al. 2013).
Accession Number:	P0AFC7
Protein Name:	NUOB aka B2287
Length:	220
Molecular Weight:	25056.00
Species:	Escherichia coli [83333]
Location¹ / Topology² / Orientation³:	Cell inner membrane¹ / Peripheral membrane protein² / Cytoplasmic side³
Substrate	hydron

RefSeq:	AP_002885.1 NP_416790.1
Entrez Gene ID:	946738
Pfam:	PF01058
BioCyc:	EcoCyc:NUOB-MONOMER ECOL168927:B2287-MONOMER MetaCyc:NUOB-MONOMER
KEGG:	ecj:JW5875 eco:b2287
Gene Ontology GO:0045272 C:plasma membrane respiratory chain complex I GO:0051539 F:4 iron, 4 sulfur cluster binding GO:0005506 F:iron ion binding GO:0008137 F:NADH dehydrogenase (ubiquinone) activity GO:0015453 F:oxidoreduction-driven active transmembrane ... GO:0048038 F:quinone binding GO:0009060 P:aerobic respiration GO:0009061 P:anaerobic respiration GO:0015990 P:electron transport coupled proton transport GO:0055114 P:oxidation reduction GO:0019684 P:photosynthesis, light reaction
References (6) [1] “The gene locus of the proton-translocating NADH: ubiquinone oxidoreductase in Escherichia coli. Organization of the 14 genes and relationship between the derived proteins and subunits of mitochondrial complex I.” Weidner U.et.al. 7690854 [2] “Construction of a contiguous 874-kb sequence of the Escherichia coli-K12 genome corresponding to 50.0-68.8 min on the linkage map and analysis of its sequence features.” Yamamoto Y.et.al. 9205837 [3] “The complete genome sequence of Escherichia coli K-12.” Blattner F.R.et.al. 9278503 [4] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.” Hayashi K.et.al. 16738553 [5] “Comparing the predicted and observed properties of proteins encoded in the genome of Escherichia coli K-12.” Link A.J.et.al. 9298646 [6] “Isolation and characterization of the proton-translocating NADH: ubiquinone oxidoreductase from Escherichia coli.” Leif H.et.al. 7607227

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MDYTLTRIDP NGENDRYPLQ KQEIVTDPLE QEVNKNVFMG KLNDMVNWGR KNSIWPYNFG 
61:	LSCCYVEMVT SFTAVHDVAR FGAEVLRASP RQADLMVVAG TCFTKMAPVI QRLYDQMLEP 
121:	KWVISMGACA NSGGMYDIYS VVQGVDKFIP VDVYIPGCPP RPEAYMQALM LLQESIGKER 
181:	RPLSWVVGDQ GVYRANMQSE RERKRGERIA VTNLRTPDEI

3.D.1.1.1
NADH dehydrogenase I, NuoA-N. NuoL probably comprises part of the proton pathway (Nakamaru-Ogiso et al. 2010). NuoL (ND5), NuoM (ND4) and NuoN (ND2) are all homologous to proton:sodium antiporters and may all play reoles in pumping protons using a similar mechanism (Sato et al. 2013).

Cross database links:

Gene Ontology

References (6)

External Searches:

Analyze:

3.D.1.1.1NADH dehydrogenase I, NuoA-N. NuoL probably comprises part of the proton pathway (Nakamaru-Ogiso et al. 2010). NuoL (ND5), NuoM (ND4) and NuoN (ND2) are all homologous to proton:sodium antiporters and may all play reoles in pumping protons using a similar mechanism (Sato et al. 2013).

Cross database links:

Gene Ontology

References (6)

External Searches:

Analyze:

3.D.1.1.1
NADH dehydrogenase I, NuoA-N. NuoL probably comprises part of the proton pathway (Nakamaru-Ogiso et al. 2010). NuoL (ND5), NuoM (ND4) and NuoN (ND2) are all homologous to proton:sodium antiporters and may all play reoles in pumping protons using a similar mechanism (Sato et al. 2013).