3.A.1.5.41
Oligopeptide transporter, OppABCDF/MppA/YgiS. MppA is a murein peptide receptor, and YgiS is a bile acid (e.g., cholate, deoxycholate) receptor that may use the Opp system for uptake. YgiS mRNA is degraded by the toxin, MgsR, which is regulated by the antitoxin, MgsA, and this loss of the mRNA protects the cell against bile acid stress (Kwan et al. 2015). oppA translation is activated by MicF through a mechanism of
action involving facilitated access to a translation-enhancing region in
oppA 5'UTR. MicF activation of oppA translation depends on cross-regulation by negative trans-acting effectors, the GcvB sRNA and the RNA chaperone protein Hfq (Carrier et al. 2023).
|
| Accession Number: | P0AFH6 |
|---|
| Protein Name: | Oligopeptide transport system permease protein OppC |
|---|
| Length: | 302 |
|---|
| Molecular Weight: | 33022.00 |
|---|
| Species: | Escherichia coli (strain K12) [83333] |
|---|
| Number of TMSs: | 6 |
|---|
| Location1 / Topology2 / Orientation3: |
Cell inner membrane1 / Multi-pass membrane protein2 |
|---|
| Substrate |
oligopeptide |
|---|
1: MMLSKKNSET LENFSEKLEV EGRSLWQDAR RRFMHNRAAV ASLIVLVLIA LFVILAPMLS
61: QFAYDDTDWA MMSSAPDMES GHYFGTDSSG RDLLVRVAIG GRISLMVGVA AALVAVVVGT
121: LYGSLSGYLG GKVDSVMMRL LEILNSFPFM FFVILLVTFF GQNILLIFVA IGMVSWLDMA
181: RIVRGQTLSL KRKEFIEAAQ VGGVSTSGIV IRHIVPNVLG VVVVYASLLV PSMILFESFL
241: SFLGLGTQEP LSSWGALLSD GANSMEVSPW LLLFPAGFLV VTLFCFNFIG DGLRDALDPK
301: DR