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3.A.1.11.1 Polyamine (putrescine/spermidine) uptake porter. Plays a role in biofilm formation (Zhang et al. 2013). Spermidine-preferring (Igarashi and Kashiwagi 1996).
Accession Number:	P0AFK4
Protein Name:	Spermidine/putrescine transport system permease protein PotB aka B1125
Length:	275
Molecular Weight:	31062.00
Species:	Escherichia coli [83333]
Number of TMSs:	6
Location¹ / Topology² / Orientation³:	Cell inner membrane¹ / Multi-pass membrane protein²
Substrate	spermidine, putrescine

RefSeq:	AP_001751.1 NP_415643.3
Entrez Gene ID:	945692
Pfam:	PF00528
BioCyc:	EcoCyc:POTB-MONOMER ECOL168927:B1125-MONOMER
KEGG:	ecj:JW1111 eco:b1125
Gene Ontology GO:0016021 C:integral to membrane GO:0005886 C:plasma membrane GO:0015417 F:polyamine-transporting ATPase activity GO:0015846 P:polyamine transport
References (5) [1] “Characteristics of the gene for a spermidine and putrescine transport system that maps at 15 min on the Escherichia coli chromosome.” Furuchi T.et.al. 1939142 [2] “A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 12.7-28.0 min region on the linkage map.” Oshima T.et.al. 8905232 [3] “The complete genome sequence of Escherichia coli K-12.” Blattner F.R.et.al. 9278503 [4] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.” Hayashi K.et.al. 16738553 [5] “Global topology analysis of the Escherichia coli inner membrane proteome.” Daley D.O.et.al. 15919996

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

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FASTA formatted sequence

1:	MIVTIVGWLV LFVFLPNLMI IGTSFLTRDD ASFVKMVFTL DNYTRLLDPL YFEVLLHSLN 
61:	MALIATLACL VLGYPFAWFL AKLPHKVRPL LLFLLIVPFW TNSLIRIYGL KIFLSTKGYL 
121:	NEFLLWLGVI DTPIRIMFTP SAVIIGLVYI LLPFMVMPLY SSIEKLDKPL LEAARDLGAS 
181:	KLQTFIRIII PLTMPGIIAG CLLVMLPAMG LFYVSDLMGG AKNLLIGNVI KVQFLNIRDW 
241:	PFGAATSITL TIVMGLMLLV YWRASRLLNK KVELE

3.A.1.11.1
Polyamine (putrescine/spermidine) uptake porter. Plays a role in biofilm formation (Zhang et al. 2013). Spermidine-preferring (Igarashi and Kashiwagi 1996).

Cross database links:

Gene Ontology

References (5)

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3.A.1.11.1Polyamine (putrescine/spermidine) uptake porter. Plays a role in biofilm formation (Zhang et al. 2013). Spermidine-preferring (Igarashi and Kashiwagi 1996).

Cross database links:

Gene Ontology

References (5)

External Searches:

Analyze:

3.A.1.11.1
Polyamine (putrescine/spermidine) uptake porter. Plays a role in biofilm formation (Zhang et al. 2013). Spermidine-preferring (Igarashi and Kashiwagi 1996).