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3.A.1.11.1
Polyamine (putrescine/spermidine) uptake porter.  Plays a role in biofilm formation (Zhang et al. 2013).  Spermidine-preferring (Igarashi and Kashiwagi 1996).

Accession Number:P0AFK9
Protein Name:Spermidine/putrescine-binding periplasmic protein PotD aka B1123
Length:348
Molecular Weight:38867.00
Species:Escherichia coli [83333]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Periplasm1
Substrate spermidine, putrescine

Cross database links:

RefSeq: AP_001749.1    NP_415641.1   
Entrez Gene ID: 945682   
Pfam: PF01547   
BioCyc: EcoCyc:POTD-MONOMER    ECOL168927:B1123-MONOMER   
KEGG: ecj:JW1109    eco:b1123   

Gene Ontology

GO:0030288 C:outer membrane-bounded periplasmic space
GO:0015417 F:polyamine-transporting ATPase activity
GO:0015846 P:polyamine transport

References (8)

[1] “Characteristics of the gene for a spermidine and putrescine transport system that maps at 15 min on the Escherichia coli chromosome.”  Furuchi T.et.al.   1939142
[2] “A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 12.7-28.0 min region on the linkage map.”  Oshima T.et.al.   8905232
[3] “The complete genome sequence of Escherichia coli K-12.”  Blattner F.R.et.al.   9278503
[4] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.”  Hayashi K.et.al.   16738553
[5] “Comparing the predicted and observed properties of proteins encoded in the genome of Escherichia coli K-12.”  Link A.J.et.al.   9298646
[6] “Prediction of the structural similarity between spermidine/putrescine-binding protein and maltose-binding protein.”  Matsuo Y.et.al.   8194593
[7] “Crystal structure of PotD, the primary receptor of the polyamine transport system in Escherichia coli.”  Sugiyama S.et.al.   8621624
[8] “The 1.8-A X-ray structure of the Escherichia coli PotD protein complexed with spermidine and the mechanism of polyamine binding.”  Sugiyama S.et.al.   8897598
Structure:
1POT   1POY     

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence 
1:	MKKWSRHLLA AGALALGMSA AHADDNNTLY FYNWTEYVPP GLLEQFTKET GIKVIYSTYE 
61:	SNETMYAKLK TYKDGAYDLV VPSTYYVDKM RKEGMIQKID KSKLTNFSNL DPDMLNKPFD 
121:	PNNDYSIPYI WGATAIGVNG DAVDPKSVTS WADLWKPEYK GSLLLTDDAR EVFQMALRKL 
181:	GYSGNTTDPK EIEAAYNELK KLMPNVAAFN SDNPANPYME GEVNLGMIWN GSAFVARQAG 
241:	TPIDVVWPKE GGIFWMDSLA IPANAKNKEG ALKLINFLLR PDVAKQVAET IGYPTPNLAA 
301:	RKLLSPEVAN DKTLYPDAET IKNGEWQNDV GAASSIYEEY YQKLKAGR