9.A.69.1.1
The Paraquot-inducible protein (PqiABC) system of intermembrane phospholipid translocation (Nakayama and Zhang-Akiyama 2016). PqiA has 417 aas and 8 TMSs in the inner membrane; PqiB has 546 aas with several repeats that are stacked on each other to form a trans-periplasmic channel for phospholipid transport, and PqiC (ymbA) has 187 aas and possibly one N-terminal TMS is located in or on the outer membrane (Nakayama and Zhang-Akiyama 2016).
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| Accession Number: | P0AFL9 |
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| Protein Name: | Paraquat-inducible protein A |
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| Length: | 417 |
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| Molecular Weight: | 46463.00 |
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| Species: | Escherichia coli (strain K12) [83333] |
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| Number of TMSs: | 8 |
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| Location1 / Topology2 / Orientation3: |
Cell inner membrane1 / Multi-pass membrane protein2 |
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| Substrate |
phospholipid |
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1: MCEHHHAAKH ILCSQCDMLV ALPRLEHGQK AACPRCGTTL TVAWDAPRQR PTAYALAALF
61: MLLLSNLFPF VNMNVAGVTS EITLLEIPGV LFSEDYASLG TFFLLFVQLV PAFCLITILL
121: LVNRAELPVR LKEQLARVLF QLKTWGMAEI FLAGVLVSFV KLMAYGSIGV GSSFLPWCLF
181: CVLQLRAFQC VDRRWLWDDI APMPELRQPL KPGVTGIRQG LRSCSCCTAI LPADEPVCPR
241: CSTKGYVRRR NSLQWTLALL VTSIMLYLPA NILPIMVTDL LGSKMPSTIL AGVILLWSEG
301: SYPVAAVIFL ASIMVPTLKM IAIAWLCWDA KGHGKRDSER MHLIYEVVEF VGRWSMIDVF
361: VIAVLSALVR MGGLMSIYPA MGALMFALVV IMTMFSAMTF DPRLSWDRQP ESEHEES