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Accession Number: | P0AGI8 |
Protein Name: | Trk system potassium uptake protein TrkA aka B3290 |
Length: | 458 |
Molecular Weight: | 50368.00 |
Species: | Escherichia coli [83333] |
Location1 / Topology2 / Orientation3: | Cell inner membrane1 / Peripheral membrane protein2 / Cytoplasmic side3 |
Substrate | potassium(1+) |
Cross database links:
RefSeq: | AP_004501.1 NP_417748.1 |
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Entrez Gene ID: | 947788 |
Pfam: | PF02080 PF02254 |
BioCyc: | EcoCyc:TRKA-MONOMER ECOL168927:B3290-MONOMER |
KEGG: | ecj:JW3251 eco:b3290 |
Gene Ontology
GO:0005886
C:plasma membrane
GO:0005488
F:binding
GO:0003824
F:catalytic activity
GO:0008324
F:cation transmembrane transporter activity
GO:0008152
P:metabolic process
GO:0006813
P:potassium ion transport
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References (6)[1] “NAD+ binding to the Escherichia coli K(+)-uptake protein TrkA and sequence similarity between TrkA and domains of a family of dehydrogenases suggest a role for NAD+ in bacterial transport.” Schloesser A.et.al. 8412700 [2] “Characterization of the Thermus thermophilus locus encoding peptide deformylase and methionyl-tRNA(fMet) formyltransferase.” Meinnel T.et.al. 7961514 [3] “The complete genome sequence of Escherichia coli K-12.” Blattner F.R.et.al. 9278503 [4] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.” Hayashi K.et.al. 16738553 [5] “A survey of polypeptide deformylase function throughout the eubacterial lineage.” Mazel D.et.al. 9086272 [6] “K+-transport protein TrkA of Escherichia coli is a peripheral membrane protein that requires other trk gene products for attachment to the cytoplasmic membrane.” Bossemeyer D.et.al. 2674131
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External Searches:
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Analyze:
Predict TMSs (Predict number of transmembrane segments) | ||||
FASTA formatted sequence |
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1: MKIIILGAGQ VGGTLAENLV GENNDITVVD TNGERLRTLQ DKFDLRVVQG HGSHPRVLRE 61: AGADDADMLV AVTSSDETNM VACQVAYSLF NTPNRIARIR SPDYVRDADK LFHSDAVPID 121: HLIAPEQLVI DNIYRLIEYP GALQVVNFAE GKVSLAVVKA YYGGPLIGNA LSTMREHMPH 181: IDTRVAAIFR HDRPIRPQGS TIVEAGDEVF FIAASQHIRA VMSELQRLEK PYKRIMLVGG 241: GNIGAGLARR LEKDYSVKLI ERNQQRAAEL AEKLQNTIVF FGDASDQELL AEEHIDQVDL 301: FIAVTNDDEA NIMSAMLAKR MGAKKVMVLI QRRAYVDLVQ GSVIDIAISP QQATISALLS 361: HVRKADIVGV SSLRRGVAEA IEAVAHGDES TSRVVGRVID EIKLPPGTII GAVVRGNDVM 421: IANDNLRIEQ GDHVIMFLTD KKFITDVERL FQPSPFFL