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2.A.38.1.1
K+ uptake transporter (K+:H+ symporter), TrkHA. The 3-d structure of TrkH is known (Cao et al. 2011).  Molecular dynamics simulations of TrkH have been reported (Domene and Furini, 2012).  TrkA, which forms a tertameric ring that needs to bind ATP to activate transport, interacts with the Enzyme IIANtr of the PTS (TC# 4.A) which inhibits transport (Lee et al. 2007).

Accession Number:P0AGI8
Protein Name:Trk system potassium uptake protein TrkA aka B3290
Length:458
Molecular Weight:50368.00
Species:Escherichia coli [83333]
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Peripheral membrane protein2 / Cytoplasmic side3
Substrate potassium(1+)

Cross database links:

RefSeq: AP_004501.1    NP_417748.1   
Entrez Gene ID: 947788   
Pfam: PF02080    PF02254   
BioCyc: EcoCyc:TRKA-MONOMER    ECOL168927:B3290-MONOMER   
KEGG: ecj:JW3251    eco:b3290   

Gene Ontology

GO:0005886 C:plasma membrane
GO:0005488 F:binding
GO:0003824 F:catalytic activity
GO:0008324 F:cation transmembrane transporter activity
GO:0008152 P:metabolic process
GO:0006813 P:potassium ion transport

References (6)

[1] “NAD+ binding to the Escherichia coli K(+)-uptake protein TrkA and sequence similarity between TrkA and domains of a family of dehydrogenases suggest a role for NAD+ in bacterial transport.”  Schloesser A.et.al.   8412700
[2] “Characterization of the Thermus thermophilus locus encoding peptide deformylase and methionyl-tRNA(fMet) formyltransferase.”  Meinnel T.et.al.   7961514
[3] “The complete genome sequence of Escherichia coli K-12.”  Blattner F.R.et.al.   9278503
[4] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.”  Hayashi K.et.al.   16738553
[5] “A survey of polypeptide deformylase function throughout the eubacterial lineage.”  Mazel D.et.al.   9086272
[6] “K+-transport protein TrkA of Escherichia coli is a peripheral membrane protein that requires other trk gene products for attachment to the cytoplasmic membrane.”  Bossemeyer D.et.al.   2674131

External Searches:

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MKIIILGAGQ VGGTLAENLV GENNDITVVD TNGERLRTLQ DKFDLRVVQG HGSHPRVLRE 
61:	AGADDADMLV AVTSSDETNM VACQVAYSLF NTPNRIARIR SPDYVRDADK LFHSDAVPID 
121:	HLIAPEQLVI DNIYRLIEYP GALQVVNFAE GKVSLAVVKA YYGGPLIGNA LSTMREHMPH 
181:	IDTRVAAIFR HDRPIRPQGS TIVEAGDEVF FIAASQHIRA VMSELQRLEK PYKRIMLVGG 
241:	GNIGAGLARR LEKDYSVKLI ERNQQRAAEL AEKLQNTIVF FGDASDQELL AEEHIDQVDL 
301:	FIAVTNDDEA NIMSAMLAKR MGAKKVMVLI QRRAYVDLVQ GSVIDIAISP QQATISALLS 
361:	HVRKADIVGV SSLRRGVAEA IEAVAHGDES TSRVVGRVID EIKLPPGTII GAVVRGNDVM 
421:	IANDNLRIEQ GDHVIMFLTD KKFITDVERL FQPSPFFL