8.B.21.1.11
γ-conotoxin PiVIIA of 25 aas. Micromolar concentrations of PiVIIA increased the magnitude of the
macroscopic calcium current in DRG neurons from rats. An increase, even
modest of the calcium current, may have a significant impact on the
excitability and electrical activity of neurons, and may set up PiVIIA
as a member of the pharmacological family of the gamma-conotoxins (Bernáldez et al. 2016).
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| Accession Number: | P0DOW6 |
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| Protein Name: | Gamma-conotoxin PiVIIA |
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| Length: | 25 |
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| Molecular Weight: | 2999.00 |
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| Species: | Conus princeps (Prince cone) [101311] |
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| Location1 / Topology2 / Orientation3: |
Secreted1 |
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| Substrate |
|
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1: CDAPTHYCTN YWECCSGYCE HSHCW