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1.G.10.1.1 The herpes envelope glycoprotein class III membrane fusion system including glycoproteins gB, gD, gH and gL. There are two fusion peptides of 8 aas each that form a bipartite system (Apellániz et al. 2014; Feng and Jia 2016).
Accession Number:	P10185
Protein Name:	Envelope glycoprotein L
Length:	224
Molecular Weight:	24934.00
Species:	Human herpesvirus 1 (strain 17) (HHV-1) [10299]
Number of TMSs:	1
Location¹ / Topology² / Orientation³:	Virion membrane¹ / Peripheral membrane protein² / Extracellular side³
Substrate	molecule

Entrez Gene ID:	2703393
Pfam:	PF12524 PF05259
Gene Ontology GO:0020002 C:host cell plasma membrane GO:0016020 C:membrane GO:0055036 C:virion membrane
References (7) [1] “The complete DNA sequence of the long unique region in the genome of herpes simplex virus type 1.” McGeoch D.J.et.al. 2839594 [2] “The DNA sequences of the long repeat region and adjoining parts of the long unique region in the genome of herpes simplex virus type 1.” Perry L.J.et.al. 2846760 [3] “Determination and analysis of the DNA sequence of highly attenuated herpes simplex virus type 1 mutant HF10, a potential oncolytic virus.” Ushijima Y.et.al. 17218138 [4] “Structure-function analysis of herpes simplex virus type 1 gD and gH-gL: clues from gDgH chimeras.” Cairns T.M.et.al. 12767993 [5] “Comprehensive characterization of extracellular herpes simplex virus type 1 virions.” Loret S.et.al. 18596102 [6] “Herpes simplex virus gD forms distinct complexes with fusion executors gB and gH/gL in part through the C-terminal profusion domain.” Gianni T.et.al. 19386594 [7] “Insertional mutations in herpes simplex virus 1 gL identify functional domains for association with gH and for membrane fusion.” Fan Q.et.al. 19726507

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FASTA formatted sequence

1:	MGILGWVGLI AVGVLCVRGG LPSTEYVIRS RVAREVGDIL KVPCVPLPSD DLDWRYETPS 
61:	AINYALIDGI FLRYHCPGLD TVLWDRHAQK AYWVNPFLFV AGFLEDLSYP AFPANTQETE 
121:	TRLALYKEIR QALDSRKQAA SHTPVKAGCV NFDYSRTRRC VGRQDLGPTN GTSGRTPVLP 
181:	PDDEAGLQPK PLTTPPPIIA TSDPTPRRDA ATKSRRRRPH SRRL

1.G.10.1.1
The herpes envelope glycoprotein class III membrane fusion system including glycoproteins gB, gD, gH and gL. There are two fusion peptides of 8 aas each that form a bipartite system (Apellániz et al. 2014; Feng and Jia 2016).

Cross database links:

Gene Ontology

References (7)

External Searches:

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1.G.10.1.1The herpes envelope glycoprotein class III membrane fusion system including glycoproteins gB, gD, gH and gL. There are two fusion peptides of 8 aas each that form a bipartite system (Apellániz et al. 2014; Feng and Jia 2016).

Cross database links:

Gene Ontology

References (7)

External Searches:

Analyze:

1.G.10.1.1
The herpes envelope glycoprotein class III membrane fusion system including glycoproteins gB, gD, gH and gL. There are two fusion peptides of 8 aas each that form a bipartite system (Apellániz et al. 2014; Feng and Jia 2016).