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3.A.2.2.5
H -translocating V-type ATPase (Dettmer et al., 2006). The mung bean (Phaseolus aureus) subunits a and c (c' and c") alone catalyzes passive channel-mediated proton flux, but the a,c,d complex does not (Ouyang et al., 2008).  A 4 TMS c-subunit of Tamarix hispida (onion), almost identical to the c-subunit of the A. thaliana homologue, plays a stress tolerance role in response to salt, drought, UV, oxidation, heat, cold, and heavy metals (Gao et al. 2011). The VHA-H subunit is up-regluated upon high salt stress conditions (Yang et al. 2018). The VHAc`1 protein seems to play an important role in plant stress tolerance (Wang et al. 2020).

Accession Number:P11574
Protein Name:V-type proton ATPase subunit B1
Length:486
Molecular Weight:54108.00
Species:Arabidopsis thaliana (Mouse-ear cress) [3702]
Location1 / Topology2 / Orientation3: Vacuole membrane1 / Peripheral membrane protein2
Substrate hydron

Cross database links:

Entrez Gene ID: 843934   
Pfam: PF00006    PF00306    PF02874   
KEGG: ath:AT1G76030   

Gene Ontology

GO:0009507 C:chloroplast
GO:0005886 C:plasma membrane
GO:0033180 C:proton-transporting V-type ATPase, V1 domain
GO:0005774 C:vacuolar membrane
GO:0046933 F:hydrogen ion transporting ATP synthase activity, rotational mechanism
GO:0046961 F:proton-transporting ATPase activity, rotational mechanism
GO:0015986 P:ATP synthesis coupled proton transport
GO:0010255 P:glucose mediated signaling pathway
GO:0046686 P:response to cadmium ion

References (5)

[1] “cDNA sequence and homologies of the '57-kDa' nucleotide-binding subunit of the vacuolar ATPase from Arabidopsis.”  Manolson M.F.et.al.   2903860
[2] “Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.”  Theologis A.et.al.   11130712
[3] “Empirical analysis of transcriptional activity in the Arabidopsis genome.”  Yamada K.et.al.   14593172
[4] “Further progress towards a catalogue of all Arabidopsis genes: analysis of a set of 5000 non-redundant ESTs.”  Cooke R.et.al.   8580968
[5] “A simple nomenclature for a complex proton pump: VHA genes encode the vacuolar H(+)-ATPase.”  Sze H.et.al.   11950611

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence 
1:	MGTNDLDIEE GTLEIGMEYR TVSGVAGPLV ILDKVKGPKY QEIVNIRLGD GSTRRGQVLE 
61:	VDGEKAVVQV FEGTSGIDNK FTTVQFTGEV LKTPVSLDML GRIFNGSGKP IDNGPPILPE 
121:	AYLDISGSSI NPSERTYPEE MIQTGISTID VMNSIARGQK IPLFSAAGLP HNEIAAQICR 
181:	QAGLVKRLEK TVDLLEDHGE DNFAIVFAAM GVNMETAQFF KRDFEENGSM ERVTLFLNLA 
241:	NDPTIERIIT PRIALTTAEY LAYECGKHVL VILTDMSSYA DALREVSAAR EEVPGRRGYP 
301:	GYMYTDLATI YERAGRIEGR KGSITQIPIL TMPNDDITHP TPDLTGYITE GQIYIDRQLH 
361:	NRQIYPPINV LPSLSRLMKS AIGEGMTRKD HSDVSNQLYA NYAIGKDVQA MKAVVGEEAL 
421:	SSEDLLYLEF LDKFERKFVM QGAYDTRNIF QSLDLAWTLL RIFPRELLHR IPAKTLDQFY 
481:	SRDSTS