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3.A.1.6.1
Sulfate/thiosulfate porter

Accession Number:P16701
Protein Name:CysT aka CysU aka B2424
Length:277
Molecular Weight:30292.00
Species:Escherichia coli [83333]
Number of TMSs:6
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate sulfate, thiosulfate(2-)

Cross database links:

RefSeq: AP_003018.1    NP_416919.1   
Entrez Gene ID: 946882   
Pfam: PF00528   
BioCyc: EcoCyc:CYST-MONOMER    ECOL168927:B2424-MONOMER   
KEGG: ecj:JW2417    eco:b2424   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0015116 F:sulfate transmembrane transporter activity
GO:0015563 F:uptake transmembrane transporter activity
GO:0008272 P:sulfate transport

References (6)

[1] “Sulfate and thiosulfate transport in Escherichia coli K-12: nucleotide sequence and expression of the cysTWAM gene cluster.”  Sirko A.et.al.   2188958
[2] “Construction of a contiguous 874-kb sequence of the Escherichia coli-K12 genome corresponding to 50.0-68.8 min on the linkage map and analysis of its sequence features.”  Yamamoto Y.et.al.   9205837
[3] “The complete genome sequence of Escherichia coli K-12.”  Blattner F.R.et.al.   9278503
[4] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.”  Hayashi K.et.al.   16738553
[5] “Sulfate and thiosulfate transport in Escherichia coli K-12: identification of a gene encoding a novel protein involved in thiosulfate binding.”  Hryniewicz M.M.et.al.   2188959
[6] “Global topology analysis of the Escherichia coli inner membrane proteome.”  Daley D.O.et.al.   15919996

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence 
1:	MFAVSSRRVL PGFTLSLGTS LLFVCLILLL PLSALVMQLA QMSWAQYWEV ITNPQVVAAY 
61:	KVTLLSAFVA SIFNGVFGLL MAWILTRYRF PGRTLLDALM DLPFALPTAV AGLTLASLFS 
121:	VNGFYGEWLA KFDIKVTYTW LGIAVAMAFT SIPFVVRTVQ PVLEELGPEY EEAAETLGAT 
181:	RWQSFCKVVL PELSPALVAG VALSFTRSLG EFGAVIFIAG NIAWKTEVTS LMIFVRLQEF 
241:	DYPAASAIAS VILAASLLLL FSINTLQSRF GRRVVGH