1.K.1.1.1
Baseplate structural protein complex (GP5 is a lysozyme showing limited similarity to ComA of Neisseria species (3.A.11.2.1)) plus Gp18 tail sheath protein of phage T4. Gp5 (575 aas), the baseplate hub subunit, contains (1) an N-terminal GP5_OB domain, (2) a central lysozyme domain, and (3) a C-terminal domain of ~200 aas with repeat units that resemble BigA (1.B.12.5.5; residues 400-600) and ComA (3.A.11.2.1; residues 400-600). Twenty proteins comprise the entire tail complex of T4. See Rossmann et al. 2004 and Leiman et al. 2010) for tabulation of the properties and evidence concerning the functions of these constituents. gp27 and gp29 may comprise the transmembrane channel (Hu et al. 2015). The tail complex of T4 resembles the type VI protein secretion systems (TC# 3.A.23) of enteric bacteria (Shneider et al. 2013).
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| Accession Number: | P19060 |
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| Protein Name: | Baseplate structural protein Gp6 |
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| Length: | 660 |
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| Molecular Weight: | 74429.00 |
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| Species: | Enterobacteria phage T4 [10665] |
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| Location1 / Topology2 / Orientation3: |
Virion1 |
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| Substrate |
deoxyribonucleic acid |
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1: MANTPVNYQL TRTANAIPEI FVGGTFAEIK QNLIEWLNGQ NEFLDYDFEG SRLNVLCDLL
61: AYNTLYIQQF GNAAVYESFM RTANLRSSVV QAAQDNGYLP TSKSAAQTEI MLTCTDALNR
121: NYITIPRGTR FLAYAKDTSV NPYNFVSRED VIAIRDKNNQ YFPRLKLAQG RIVRTEIIYD
181: KLTPIIIYDK NIDRNQVKLY VDGAEWINWT RKSMVHAGST STIYYMRETI DGNTEFYFGE
241: GEISVNASEG ALTANYIGGL KPTQNSTIVI EYISTNGADA NGAVGFSYAD TLTNITVINI
301: NENPNDDPDF VGADGGGDPE DIERIRELGT IKRETQQRCV TATDYDTFVS ERFGSIIQAV
361: QTFTDSTKPG YAFIAAKPKS GLYLTTVQRE DIKNYLKDYN LAPITPSIIS PNYLFIKTNL
421: KVTYALNKLQ ESEQWLEGQI IDKIDRYYTE DVEIFNSSFA KSKMLTYVDD ADHSVIGSSA
481: TIQMVREVQN FYKTPEAGIK YNNQIKDRSM ESNTFSFNSG RKVVNPDTGL EEDVLYDVRI
541: VSTDRDSKGI GKVIIGPFAS GDVTENENIQ PYTGNDFNKL ANSDGRDKYY VIGEINYPAD
601: VIYWNIAKIN LTSEKFEVQT IELYSDPTDD VIFTRDGSLI VFENDLRPQY LTIDLEPISQ