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3.A.2.1.2
Na+-translocating F-type ATPase/ATP synthase of 8 subunits.  The Fo-a subunit plays a role in Na+ transport. It forms half channels that allow Na+ to enter and leave the buried carboxyl group on the Fo-c subunits. The essential Arg residue, R226, which faces the carboxyl group of Fo-c subunits in the middle of transmembrane helix 5 of the Fo-a subunit, separates the cytoplasmic side and periplasmic half-channels (Mitome et al. 2017). Residues that contribute to the integrity of the Na+ half channels have been identified; both half channels are present in the Fo-a subunit (Mitome et al. 2017).

Accession Number:P21903
Protein Name:ATP6 aka ATPB aka UNCB
Length:289
Molecular Weight:32224.00
Species:Propionigenium modestum [2333]
Number of TMSs:6
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate sodium(1+)

Cross database links:

Pfam: PF00119   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0045263 C:proton-transporting ATP synthase complex, c...
GO:0046933 F:hydrogen ion transporting ATP synthase acti...
GO:0042777 P:plasma membrane ATP synthesis coupled proto...
GO:0006814 P:sodium ion transport

References (4)

[1] “Sequence of subunits a and b of the sodium ion translocating adenosine triphosphate synthase of Propionigenium modestum.”  Kaim G.W.et.al.   2174545
[2] “Cloning, sequencing and in vivo expression of genes encoding the F0 part of the sodium-ion-dependent ATP synthase of Propionigenium modestum in Escherichia coli.”  Kaim G.W.et.al.   1386022
[3] “Nucleotide sequence of the F0 subunits of the sodium dependent F1F0 ATPase of Propionigenium modestum.”  Esser U.et.al.   2170948
[4] “Characterization of the genes coding for the F1F0 subunits of the sodium dependent ATPase of Propionigenium modestum.”  Krumholz L.R.et.al.   1533602

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence 
1:	MKKMGPIILA VVIAIGTFAL KMMGVIGFKT PPLVEGPKIM FYVPLPEAMH DFPFAMEMAS 
61:	GVYGFPVTIT VISTWFVMLF LIMVFRWSSK NLEVVPERKQ AFFETIYGFL DDLYGQLLGN 
121:	WKKKYFTYIG TLFLFLLISN IVSFFPIPGF SSENGVFSIA PALRTPTADL NTTVGLALLT 
181:	TYSFIAASFR TSGFFGFFKG LFEPMPLMFP INLAGEFAKP TNISIRLFGN MFAGMVILGL 
241:	LYKAAPVLIP APLHLYFDLF SGVVQSFVFI MLTMVYIQGS IGDAEYLED