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3.A.2.1.2
Na+-translocating F-type ATPase/ATP synthase of 8 subunits.  The Fo-a subunit plays a role in Na+ transport. It forms half channels that allow Na+ to enter and leave the buried carboxyl group on the Fo-c subunits. The essential Arg residue, R226, which faces the carboxyl group of Fo-c subunits in the middle of transmembrane helix 5 of the Fo-a subunit, separates the cytoplasmic side and periplasmic half-channels (Mitome et al. 2017). Residues that contribute to the integrity of the Na+ half channels have been identified; both half channels are present in the Fo-a subunit (Mitome et al. 2017).

Accession Number:P21904
Protein Name:ATPF aka UNCF
Length:168
Molecular Weight:19201.00
Species:Propionigenium modestum [2333]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Single-pass membrane protein2
Substrate sodium(1+)

Cross database links:

Pfam: PF00430   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0045263 C:proton-transporting ATP synthase complex, c...
GO:0046933 F:hydrogen ion transporting ATP synthase acti...
GO:0015986 P:ATP synthesis coupled proton transport
GO:0006814 P:sodium ion transport

References (4)

[1] “Sequence of subunits a and b of the sodium ion translocating adenosine triphosphate synthase of Propionigenium modestum.”  Kaim G.W.et.al.   2174545
[2] “Cloning, sequencing and in vivo expression of genes encoding the F0 part of the sodium-ion-dependent ATP synthase of Propionigenium modestum in Escherichia coli.”  Kaim G.W.et.al.   1386022
[3] “Nucleotide sequence of the F0 subunits of the sodium dependent F1F0 ATPase of Propionigenium modestum.”  Esser U.et.al.   2170948
[4] “N-terminal amino acid sequences of the subunits of the Na(+)-translocating F1F0 ATPase from Propionigenium modestum.”  Gerike U.et.al.   8422943

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence 
1:	MAPQNMPAVS IDINMFWQII NFLILMFFFK KYFQKPIAKV LDARKEKIAN DLKQAEIDKE 
61:	MAAKANGEAQ GIVKSAKTEA NEMLLRAEKK ADERKETILK EANTQREKML KSAEVEIEKM 
121:	KEQARKELQL EVTDLAVKLA EKMINEKVDA KIGANLLDQF IGEVGEEK