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3.D.1.6.2
The fungal H+ translocating NADH dehydrogenase (NDH) complex (38 subunits; 35 included here) (Cardol et al., 2004).  The high resolution (3.6 - 3.9 Å) structure of the mitochondrial Yarrowia lipolytica enzyme, showing all central subunits that execute the bioenergetic functions, has been solved (see discussion for TC# 3.A.1 and Zickermann et al. 2015). The subunit inventory of mitochondrial complex I from the obligate aerobic yeast Yarrowia lipolytica involved a total of 37 subunits (Abdrakhmanova et al. 2004).

Accession Number:P22142
Protein Name:49 (NuoD)
Length:478
Molecular Weight:54019.00
Species:Neurospora crassa [5141]
Location1 / Topology2 / Orientation3: Mitochondrion inner membrane1 / Peripheral membrane protein2 / Matrix side3
Substrate hydron

Cross database links:

RefSeq: XP_965665.2   
Entrez Gene ID: 3881799   
Pfam: PF00346   
KEGG: ncr:NCU02534   

Gene Ontology

GO:0005743 C:mitochondrial inner membrane
GO:0070469 C:respiratory chain
GO:0051539 F:4 iron, 4 sulfur cluster binding
GO:0046872 F:metal ion binding
GO:0051287 F:NAD or NADH binding
GO:0008137 F:NADH dehydrogenase (ubiquinone) activity
GO:0048038 F:quinone binding
GO:0022900 P:electron transport chain
GO:0006810 P:transport

References (2)

[1] “The 49 K subunit of NADH: ubiquinone reductase (complex I) from Neurospora crassa mitochondria: primary structure of the gene and the protein.”  Preis D.et.al.   2147127
[2] “The genome sequence of the filamentous fungus Neurospora crassa.”  Galagan J.E.et.al.   12712197

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence 
1:	MATTLFRLAG RNAKRHCMRQ STTIAHNLNS TRAFSASALR RYAEPSYEGQ GTRLVPTGDD 
61:	FAPNNDLYGL EALKADGAPR VPPQDHILAR KVRHYTVNFG PQHPAAHGVL RLILELKGEE 
121:	IVRADPHVGL LHRGTEKLCE YRTYLQALPY FDRLDYVSMM TNEQCFALAV EKLLNVEIPE 
181:	RAKWIRTMFA EITRILNHLM SVLSHAMDVG ALTPFLWGFE EREKLMEFYE RVSGARLHAA 
241:	YVRPGGVHQD IPLGLLDDIY MWATQFGDRI DETEEMLTDN RIWIDRLRGI GVVSAADALN 
301:	LSFTGVMLRG SGVPWDIRKS QPYDAYDQVE FDVPVGINGD CYDRYLCRME EFRQSLRIIH 
361:	QCLNKMPAGP VRVEDYKISP PPRSAMKENM EALIHHFLLY TKGYAVPPGD TYSAIEAPKG 
421:	EMGVYVVSDG SERPYRVHIR APGFAHLGGF DHLSRGHMLA DAVAVIGTMD LVFGEVDR