Search TCDB: (?)
TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


3.A.15.2.1
The pilin secretion/fimbrial assembly system. The PilB and PilT ATPases act antagonistically in Type IV pilus function in Myxococcus xanthus. ATP binding and hydrolysis by PilT are essential for T4P extension while ATP binding and hydrolysis by PilB are essential for T4P retraction. Thus, PilB and PilT act at distinct steps in the T4P extension/retraction cycle (Jakovljevic et al., 2008).

Accession Number:P22609
Protein Name:PilC aka PA4527
Length:374
Molecular Weight:40887.00
Species:Pseudomonas aeruginosa [287]
Number of TMSs:4
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate

Cross database links:

Pfam: PF00482   
BioCyc: PAER208964:PA4527-MONOMER   
KEGG: pae:PA4527   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0015627 C:type II protein secretion system complex
GO:0008565 F:protein transporter activity
GO:0015628 P:protein secretion by the type II secretion ...

References (2)

[1] “Products of three accessory genes, pilB, pilC, and pilD, are required for biogenesis of Pseudomonas aeruginosa pili.”  Nunn D.et.al.   1971619
[2] “Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen.”  Stover C.K.et.al.   10984043

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence 
1:	MLVKAHLRKQ GINPLKVRKK GISLLGAGKK VKPMDIALFT RQMATMMGAG VPLLQSFDII 
61:	GEGFDNPNMR KLVDEIKQEV SSGNSLANSL RKKPQYFDEL YCNLVDAGEQ SGALENLLDR 
121:	VATYKEKTES LKAKIRKAMT YPIAVIIVAL IVSAILLIKV VPQFQSVFQG FGAELPAFTQ 
181:	MVVNLSEFLQ EWWLAVIVGV GAIGFTFKEL HKRSKKFRDT LDRTILKLPI FGGIVYKSAV 
241:	ARYARTLSTT FAAGVPLVDA LDSVSGATGN IVFKNAVSKI KQDVSTGMQL NFSMRTTSVF 
301:	PNMAIQMTAI GEESGSLDEM LSKVASYYEE EVDNAVDNLT TLMEPMIMAV LGVLVGGLIV 
361:	AMYLPIFQLG NVVG