TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


3.D.1.6.2
The fungal H+ translocating NADH dehydrogenase (NDH) complex (38 subunits; 35 included here) (Cardol et al., 2004).  The high resolution (3.6 - 3.9 Å) structure of the mitochondrial Yarrowia lipolytica enzyme, showing all central subunits that execute the bioenergetic functions, has been solved (see discussion for TC# 3.A.1 and Zickermann et al. 2015). The subunit inventory of mitochondrial complex I from the obligate aerobic yeast Yarrowia lipolytica involved a total of 37 subunits (Abdrakhmanova et al. 2004).

Accession Number:P25710
Protein Name:21.3b
Length:200
Molecular Weight:21349.00
Species:Neurospora crassa [5141]
Number of TMSs:3
Location1 / Topology2 / Orientation3: Mitochondrion inner membrane1 / Multi-pass membrane protein2
Substrate hydron

Cross database links:

RefSeq: XP_959924.1   
Entrez Gene ID: 3876046   
Pfam: PF02466   
BioCyc: NCRA-XX3-01:NCRA-XX3-01-006028-MONOMER   
KEGG: ncr:NCU02280   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005743 C:mitochondrial inner membrane
GO:0008137 F:NADH dehydrogenase (ubiquinone) activity
GO:0008565 F:protein transporter activity
GO:0055114 P:oxidation reduction
GO:0015031 P:protein transport

References (3)

[1] “cDNA and genomic DNA sequence of the 21.3 kDa subunit of NADH:ubiquinone reductase (complex I) from Neurospora crassa.”  Nehls U.et.al.   1825789
[2] “What's in the genome of a filamentous fungus? Analysis of the Neurospora genome sequence.”  Mannhaupt G.et.al.   12655011
[3] “The genome sequence of the filamentous fungus Neurospora crassa.”  Galagan J.E.et.al.   12712197

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence
1:	MAPQGDDTVF QPKDAIKSGV SGALFSGGAG LLMASLRTSM KKNNVGSMHV FTHGGGTIIS 
61:	FTLAGGIYRF AQQASANLRE KEDGWNHAIG AFLGGSVMGL RSLRFPVILG FGAMAGSVVG 
121:	AFAFSGGLTG WGRDPNVDEF ERKEAMRLNR RRPVEETLAE VGEGRGIYPP GYQERRRQRL 
181:	LEKYGVEVKP VSADPNVASA