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3.A.2.1.2
Na+-translocating F-type ATPase/ATP synthase of 8 subunits.  The Fo-a subunit plays a role in Na+ transport. It forms half channels that allow Na+ to enter and leave the buried carboxyl group on the Fo-c subunits. The essential Arg residue, R226, which faces the carboxyl group of Fo-c subunits in the middle of transmembrane helix 5 of the Fo-a subunit, separates the cytoplasmic side and periplasmic half-channels (Mitome et al. 2017). Residues that contribute to the integrity of the Na+ half channels have been identified; both half channels are present in the Fo-a subunit (Mitome et al. 2017).

Accession Number:P29706
Protein Name:ATPA aka UNCA
Length:500
Molecular Weight:54472.00
Species:Propionigenium modestum [2333]
Location1 / Topology2 / Orientation3: Cell membrane1 / Peripheral membrane protein2
Substrate sodium(1+)

Cross database links:

Pfam: PF00006    PF00306    PF02874   

Gene Ontology

GO:0005886 C:plasma membrane
GO:0045261 C:proton-transporting ATP synthase complex, c...
GO:0005524 F:ATP binding
GO:0046933 F:hydrogen ion transporting ATP synthase acti...
GO:0046961 F:proton-transporting ATPase activity, rotati...
GO:0042777 P:plasma membrane ATP synthesis coupled proto...
GO:0006814 P:sodium ion transport

References (3)

[1] “Cloning, sequencing and in vivo expression of genes encoding the F0 part of the sodium-ion-dependent ATP synthase of Propionigenium modestum in Escherichia coli.”  Kaim G.W.et.al.   1386022
[2] “In vivo synthesis of ATPase complexes of Propionigenium modestum and Escherichia coli and analysis of their function.”  Gerike U.et.al.   7556212
[3] “N-terminal amino acid sequences of the subunits of the Na(+)-translocating F1F0 ATPase from Propionigenium modestum.”  Gerike U.et.al.   8422943

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence 
1:	MKIRPEEISG IIKTEIENYK KSLDVKTSGS VVQVGDGIAR IYGLSNAKAG ELLEFPNGIT 
61:	GMALNLEENN VGAVILGDPT GVKEGDEVRA TGQIAAVGAG EALLGRVVNS LGEPIDGKGE 
121:	LKTEKMMPLD RKAYGIISRK PVHEPLQTGI KSIDGMVPIG RGQRELIIGD RQTGKTAVAL 
181:	DAIINQKDTG VKCIYVAIGQ KRSTVAQIVK RLEDAGALEY TIVVAATASE SAPLQYMAPY 
241:	TGVSMGEYFM DKGEHVLIVY DDLSKHAVAY REMSLLLKRP PGREAFPGDV FYLHSRLLER 
301:	AAKLSDEIGA GSITALPIIE TQAGDVSAYI PTNVISITDG QIFLDSQLFN SGFRPAINAG 
361:	ISVSRVGGAA QIKAMKQVAA QVKLELAQYN ELLTFAQFGS DLDKATLAQL ERGHRIMEIL 
421:	KQEQYKPFVV EEQVVSFFTV INGYLDDIAI DQVRRFEKEL LEELKDNTTI LAEIVEKKAI 
481:	KEDLDAKLRK AIEDFKKKFS