Search TCDB: (?)
TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


3.A.2.1.2
Na+-translocating F-type ATPase/ATP synthase of 8 subunits.  The Fo-a subunit plays a role in Na+ transport. It forms half channels that allow Na+ to enter and leave the buried carboxyl group on the Fo-c subunits. The essential Arg residue, R226, which faces the carboxyl group of Fo-c subunits in the middle of transmembrane helix 5 of the Fo-a subunit, separates the cytoplasmic side and periplasmic half-channels (Mitome et al. 2017). Residues that contribute to the integrity of the Na+ half channels have been identified; both half channels are present in the Fo-a subunit (Mitome et al. 2017).

Accession Number:P29710
Protein Name:ATPG aka UNCG
Length:282
Molecular Weight:31813.00
Species:Propionigenium modestum [2333]
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Peripheral membrane protein2
Substrate sodium(1+)

Cross database links:

Pfam: PF00231   

Gene Ontology

GO:0005886 C:plasma membrane
GO:0045261 C:proton-transporting ATP synthase complex, c...
GO:0005524 F:ATP binding
GO:0046933 F:hydrogen ion transporting ATP synthase acti...
GO:0046961 F:proton-transporting ATPase activity, rotati...
GO:0015986 P:ATP synthesis coupled proton transport
GO:0006814 P:sodium ion transport

References (2)

[1] “Characterization of the genes coding for the F1F0 subunits of the sodium dependent ATPase of Propionigenium modestum.”  Krumholz L.R.et.al.   1533602
[2] “N-terminal amino acid sequences of the subunits of the Na(+)-translocating F1F0 ATPase from Propionigenium modestum.”  Gerike U.et.al.   8422943

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence 
1:	MAAGKEIKSR ISSVQSTRQI TKAMEIVSST KFKKFQALVN QSKPYSGSMD KVLANLAAGI 
61:	KNERHPLFDG KTEVKRIGII VMTSDRGLCG GFNSSTLKEM EKLIVANPDK EVSVIAIGKK 
121:	GRDYCKKKDR DLKAEYIQLI PETMFDKAKE ISENIVEYFY EDIFDEVYLI YNEFISALST 
181:	ELIVKKLLPI ERIEVQDNTT YIFEPSVEDI LSSLLPKYLN IQLYQAILEN TASEHSARKN 
241:	AMKNATDNAE DMIKDLTLQY NRERQAAITQ EISEIVSGAS AL