TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


3.A.1.11.2
Putrescine porter (Igarashi and Kashiwagi 1996).

Accession Number:P31135
Protein Name:PotH aka B0856
Length:317
Molecular Weight:35490.00
Species:Escherichia coli [83333]
Number of TMSs:6
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate putrescine

Cross database links:

RefSeq: AP_001487.1    NP_415377.1   
Entrez Gene ID: 945475   
Pfam: PF00528   
BioCyc: EcoCyc:POTH-MONOMER    ECOL168927:B0856-MONOMER   
KEGG: ecj:JW0840    eco:b0856   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0015594 F:putrescine-importing ATPase activity
GO:0015847 P:putrescine transport

References (5)

[1] “Characteristics of the operon for a putrescine transport system that maps at 19 minutes on the Escherichia coli chromosome.”  Pistocchi R.et.al.   8416922
[2] “A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 12.7-28.0 min region on the linkage map.”  Oshima T.et.al.   8905232
[3] “The complete genome sequence of Escherichia coli K-12.”  Blattner F.R.et.al.   9278503
[4] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.”  Hayashi K.et.al.   16738553
[5] “Global topology analysis of the Escherichia coli inner membrane proteome.”  Daley D.O.et.al.   15919996

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence
1:	MSTLEPAAQS KPPGGFKLWL SQLQMKHGRK LVIALPYIWL ILLFLLPFLI VFKISLAEMA 
61:	RAIPPYTELM EWADGQLSIT LNLGNFLQLT DDPLYFDAYL QSLQVAAIST FCCLLIGYPL 
121:	AWAVAHSKPS TRNILLLLVI LPSWTSFLIR VYAWMGILKN NGVLNNFLLW LGVIDQPLTI 
181:	LHTNLAVYIG IVYAYVPFMV LPIYTALIRI DYSLVEAALD LGARPLKTFF TVIVPLTKGG 
241:	IIAGSMLVFI PAVGEFVIPE LLGGPDSIMI GRVLWQEFFN NRDWPVASAV AIIMLLLLIV 
301:	PIMWFHKHQQ KSVGEHG