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| Accession Number: | P32266 |
| Protein Name: | Dynamin-like GTPase MGM1, mitochondrial |
| Length: | 881 |
| Molecular Weight: | 99178.00 |
| Species: | Saccharomyces cerevisiae (Baker's yeast) [4932] |
| Number of TMSs: | 1 |
| Location1 / Topology2 / Orientation3: | Mitochondrion inner membrane1 / Peripheral membrane protein2 / Intermembrane side3 |
| Substrate | |
Cross database links:
| DIP: | DIP-8008N |
|---|---|
| RefSeq: | NP_014854.2 |
| Entrez Gene ID: | 854386 |
| Pfam: | PF00350 |
| KEGG: | sce:YOR211C |
Gene Ontology
GO:0016021
C:integral to membrane
GO:0005743
C:mitochondrial inner membrane
GO:0005758
C:mitochondrial intermembrane space
GO:0005525
F:GTP binding
GO:0003924
F:GTPase activity
GO:0005515
F:protein binding
GO:0008053
P:mitochondrial fusion
GO:0000002
P:mitochondrial genome maintenance
GO:0007006
P:mitochondrial membrane organization
GO:0000001
P:mitochondrion inheritance
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References (12)[1] “Mitochondrial DNA maintenance in yeast requires a protein containing a region related to the GTP-binding domain of dynamin.” Jones B.A.et.al. 1532158 [2] “Normal mitochondrial structure and genome maintenance in yeast requires the dynamin-like product of the MGM1 gene.” Guan K.et.al. 7916673 [3] “The nucleotide sequence of Saccharomyces cerevisiae chromosome XV.” Dujon B.et.al. 9169874 [4] “Sequence and analysis of a 33 kb fragment from the right arm of chromosome XV of the yeast Saccharomyces cerevisiae.” Galisson F.et.al. 8840505 [5] “Interactions between three common subunits of yeast RNA polymerases I and III.” Lalo D.et.al. 8516295 [6] “Processing of Mgm1 by the rhomboid-type protease Pcp1 is required for maintenance of mitochondrial morphology and of mitochondrial DNA.” Herlan M.et.al. 12707284 [7] “The yeast dynamin-like protein, Mgm1p, functions on the mitochondrial outer membrane to mediate mitochondrial inheritance.” Shepard K.A.et.al. 10037792 [8] “The intramitochondrial dynamin-related GTPase, Mgm1p, is a component of a protein complex that mediates mitochondrial fusion.” Wong E.D.et.al. 12566426 | |
| Structure: | |
External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MNASPVRLLI LRRQLATHPA ILYSSPYIKS PLVHLHSRMS NVHRSAHANA LSFVITRRSI 61: SHFPKIISKI IRLPIYVGGG MAAAGSYIAY KMEEASSFTK DKLDRIKDLG ESMKEKFNKM 121: FSGDKSQDGG HGNDGTVPTA TLIAATSLDD DESKRQGDPK DDDDEDDDDE DDENDSVDTT 181: QDEMLNLTKQ MIEIRTILNK VDSSSAHLTL PSIVVIGSQS SGKSSVLESI VGREFLPKGS 241: NMVTRRPIEL TLVNTPNSNN VTADFPSMRL YNIKDFKEVK RMLMELNMAV PTSEAVSEEP 301: IQLTIKSSRV PDLSLVDLPG YIQVEAADQP IELKTKIRDL CEKYLTAPNI ILAISAADVD 361: LANSSALKAS KAADPKGLRT IGVITKLDLV DPEKARSILN NKKYPLSMGY VGVITKTPSS 421: INRKHLGLFG EAPSSSLSGI FSKGQHGQSS GEENTNGLKQ IVSHQFEKAY FKENKKYFTN 481: CQVSTKKLRE KLIKILEISM SNALEPTSTL IQQELDDTSY LFKVEFNDRH LTPKSYLLNN 541: IDVLKLGIKE FQEKFHRNEL KSILRAELDQ KVLDVLATRY WKDDNLQDLS SSKLESDTDM 601: LYWHKKLELA SSGLTKMGIG RLSTMLTTNA ILKELDNILE STQLKNHELI KDLVSNTAIN 661: VLNSKYYSTA DQVENCIKPF KYEIDLEERD WSLARQHSIN LIKEELRQCN SRYQAIKNAV 721: GSKKLANVMG YLENESNLQK ETLGMSKLLL ERGSEAIFLD KRCKVLSFRL KMLKNKCHST 781: IEKDRCPEVF LSAVSDKLTS TAVLFLNVEL LSDFFYNFPI ELDRRLTLLG DEQVEMFAKE 841: DPKISRHIEL QKRKELLELA LEKIDSILVF KKSYKGVSKN L