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3.A.1.2.6
D-allose porter.  The structure of AlsB has been solved at 1.8 Å resolution (Chaudhuri et al. 1999). Ten residues from both the domains form 14 hydrogen bonds with the sugar. 6-Deoxy-allose, 3-deoxy-glucose and ribose bind with reduced affinity so AlbP can function as a low affinity transporter for D-ribose (Chaudhuri et al. 1999).

Accession Number:P32720
Protein Name:AlsC aka B4086
Length:326
Molecular Weight:34316.00
Species:Escherichia coli [83333]
Number of TMSs:10
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate allose

Cross database links:

RefSeq: AP_004588.1    NP_418510.1   
Entrez Gene ID: 948594   
Pfam: PF02653   
BioCyc: EcoCyc:YJCV-MONOMER    ECOL168927:B4086-MONOMER   
KEGG: ecj:JW4047    eco:b4086   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0005215 F:transporter activity
GO:0008643 P:carbohydrate transport

References (6)

[1] “Analysis of the Escherichia coli genome. IV. DNA sequence of the region from 89.2 to 92.8 minutes.”  Blattner F.R.et.al.   8265357
[2] “The complete genome sequence of Escherichia coli K-12.”  Blattner F.R.et.al.   9278503
[3] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.”  Hayashi K.et.al.   16738553
[4] “Analysis of the Escherichia coli genome VI: DNA sequence of the region from 92.8 through 100 minutes.”  Burland V.D.et.al.   7610040
[5] “The D-allose operon of Escherichia coli K-12.”  Kim C.et.al.   9401019
[6] “Global topology analysis of the Escherichia coli inner membrane proteome.”  Daley D.O.et.al.   15919996

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence 
1:	MGFTTRVKSE ASEKKPFNFA LFWDKYGTFF ILAIIVAIFG SLSPEYFLTT NNITQIFVQS 
61:	SVTVLIGMGE FFAILVAGID LSVGAILALS GMVTAKLMLA GVDPFLAAMI GGVLVGGALG 
121:	AINGCLVNWT GLHPFIITLG TNAIFRGITL VISDANSVYG FSFDFVNFFA ASVIGIPVPV 
181:	IFSLIVALIL WFLTTRMRLG RNIYALGGNK NSAFYSGIDV KFHILVVFII SGVCAGLAGV 
241:	VSTARLGAAE PLAGMGFETY AIASAIIGGT SFFGGKGRIF SVVIGGLIIG TINNGLNILQ 
301:	VQTYYQLVVM GGLIIAAVAL DRLISK