1.F.2.1.1
Yeast 8 subunit exocyst complex involved in tethering before membrane fusion between vesicles and the plasma membrane (Zárský et al. 2013). Subunits include Sec3, 1336 aas, Sec5, 971 aas, Sec6, 805 aas, Sec8, 1065 aas, Sec10, 871 aas, Sec15, 910 aas, Exo70, 623 aas and Exo84, 753 aas. Exosomes can function as nano-shuttles bearing, for example, therapeutic biomolecules (Masjedi et al. 2024).
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| Accession Number: | P32844 |
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| Protein Name: | Exocyst complex component SEC6 |
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| Length: | 805 |
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| Molecular Weight: | 93428.00 |
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| Species: | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [559292] |
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| Location1 / Topology2 / Orientation3: |
Cytoplasm1 |
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| Substrate |
molecule |
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1: MSSDPLQQVC DLIKGDLSLE RVRDIKEQLL KEKSVVEYQL NKESDKYYGE VEESLKLLNL
61: SKNSVTSIKQ QINEVNKLGN DNRFAINRYD ILFRATKLYE TVNTTSSIYD RIYNFVALME
121: HIERLLVAEL AEDALETGCP HLLEIHFLLT SARDFQEQVV VMAKEATEDA QRTVMKLFSR
181: LSGIISKFDK LLDGLTYDIV EMARAEQISL AIRLFKIYDL EEREDLRIEA IRNIIKKKEI
241: EIEKSSIKKL PNSKNTARLQ DETPKVIEYP TNKGLYQEIM SGTISTRTAP RGYKHFLING
301: INNSISEMFG EMREKYVGDQ KFDVLDNMDW IFNELIIVKE HIANCCPPHW NIFEVYFDQY
361: YKELHSLITD LVESEPETII ILDILAFDKT FQDTLKQDFG FTKSEVKSVI GDKEKETLFK
421: DYLNLIVVKM TEWIGNLEKA EFDVFLERST PPHSDSDGLL FLDGTKTCFQ MFTQQVEVAA
481: GTNQAKILVG VVERFSDLLT KRQKNWISKI SEEIKKQINY NHKYDIDPES ITPEDECPGG
541: LVEYLIAVSN DQMKAADYAV AISSKYGKLV SKVYEKQITN HLEGTLDGFA EVAQCSSLGL
601: ITLMFDDLRK PYQEIFSKTW YMGSQAQQIA DTLDEYLLDI KPQMNSVLFV NFIDNVIGET
661: IIKFLTALSF EHSFKNKNNK FLEAMKRDFE IFYQLFVKVL DGNESKDTLI TQNFTVMEFF
721: MDLSCEPIDS ILDIWQKYLE VYWDSRIDLL VGILKCRKDV SSSERKKIVQ QATEMLHEYR
781: RNMEANGVDR EPTLMRRFVL EFEKQ