9.A.63.1.1
The yeast retromer-dependent Vacuolar Protein Sorting (VPS) apparatus (Feyder et al. 2015). The sorting nexin (SNX) proteins, homologous to retromer-dependent VPS protein, Q92331, that normally function in endosomal membrane trafficking, are a major class of inclusion-associated host proteins in chlamydial infection (Paul et al. 2017). Some of the components of this system are homologous to those of the retromer complexes in animals (see 9.A.3; McNally and Cullen 2018). VPS1, a GTPase involved in membrane fusion/fission, of 704 aas, may be involved in Coenzyme Q uptake and trafficking (Guile et al. 2023). The dynamin-like GTPase Vps1 mediates Atg9 transport to the phagophore assembly site (Hu and Reggiori 2023). The yeast dynamin-like GTPase Vps1 mediates Atg9 transport to the phagophore assembly site in Saccharomyces cerevisiae (Hu and Reggiori 2023).
|
| Accession Number: | P32913 |
|---|
| Protein Name: | Vacuolar protein sorting-associated protein 17 |
|---|
| Length: | 551 |
|---|
| Molecular Weight: | 63204.00 |
|---|
| Species: | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [559292] |
|---|
| Location1 / Topology2 / Orientation3: |
Endomembrane system1 / Peripheral membrane protein2 / Cytoplasmic side3 |
|---|
| Substrate |
protein polypeptide chain |
|---|
1: MTSAVPYDPY DDLDNNPFAE PQEEDSEPAA TTTDGSSSMS EERVGTEQTA ASVQDNGTAN
61: NIQNGLGEEG NATRSKTSNE HNENQQPSQP SERVILPERS DEKKKYTLLA KVTGLERFGS
121: ATGKKENPTI IFDCSTNLPT FRKQQYKNVK KSYEEFHQLF KYLNVAIQES FVPTLPSAYT
181: TFGINSEEDR MKVTRNFQLW FNRLSQDPLI IRNEEVAFFI ESDFNTYTPI NKSKSLASGL
241: KRKTLKQLAP PYDEITELAE FRPLVKSIYV VSQSLQEKLL RVSRNRKMMV QEENAFGQDF
301: VNLDEHNKLY RRYGKILTAV GDIDSIIATM DMATLYDGLE WIVRDAYAVK EALTNRHFIM
361: RNLVQAQQNS KAKQEQARRF RSRRDINPMK IDEALRQLKA AAKNEQVLTL KLQRITSNMI
421: IERKQWISWY EEWIRSSIKE FTLRKIEYER KKLTLLERVR SDIRKADENG GLSRLGRHAV
481: SNNNSDTSQT LKGDSWTGES NRKSQIPINK IAHTEFDDEL FTEDDGYNSQ DSDTTSLNAR
541: HAASLLGMST K