9.A.63.1.1 The yeast retromer-dependent Vacuolar Protein Sorting (VPS) apparatus (Feyder et al. 2015). The sorting nexin (SNX) proteins, homologous to retromer-dependent VPS protein, Q92331, that normally function in endosomal membrane trafficking, are a major class of inclusion-associated host proteins in chlamydial infection (Paul et al. 2017). Some of the components of this system are homologous to those of the retromer complexes in animals (see 9.A.3; McNally and Cullen 2018). VPS1, a GTPase involved in membrane fusion/fission, of 704 aas, may be involved in Coenzyme Q uptake and trafficking (Guile et al. 2023). The dynamin-like GTPase Vps1 mediates Atg9 transport to the phagophore assembly site (Hu and Reggiori 2023). The yeast dynamin-like GTPase Vps1 mediates Atg9 transport to the phagophore assembly site in Saccharomyces cerevisiae (Hu and Reggiori 2023).
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Accession Number: | P32939 |
Protein Name: | GTP-binding protein YPT7 |
Length: | 208 |
Molecular Weight: | 23043.00 |
Species: | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [559292] |
Location1 / Topology2 / Orientation3: |
Vacuole1 |
Substrate |
protein polypeptide chain |
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1: MSSRKKNILK VIILGDSGVG KTSLMHRYVN DKYSQQYKAT IGADFLTKEV TVDGDKVATM
61: QVWDTAGQER FQSLGVAFYR GADCCVLVYD VTNASSFENI KSWRDEFLVH ANVNSPETFP
121: FVILGNKIDA EESKKIVSEK SAQELAKSLG DIPLFLTSAK NAINVDTAFE EIARSALQQN
181: QADTEAFEDD YNDAINIRLD GENNSCSC