Search TCDB: (?)
TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


3.A.1.5.3
Nickel porter. Histidine 416 of NikA is essential for nickel uptake (Cavazza et al., 2011).

Accession Number:P33593
Protein Name:NikD aka B3479
Length:254
Molecular Weight:26820.00
Species:Escherichia coli [83333]
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Peripheral membrane protein2
Substrate nickel(2+)

Cross database links:

DIP: DIP-10343N
RefSeq: AP_004313.1    NP_417936.1   
Entrez Gene ID: 947989   
Pfam: PF00005   
BioCyc: EcoCyc:NIKD-MONOMER    ECOL168927:B3479-MONOMER   
KEGG: ecj:JW3444    eco:b3479   

Gene Ontology

GO:0005886 C:plasma membrane
GO:0005524 F:ATP binding
GO:0016151 F:nickel ion binding
GO:0015413 F:nickel-transporting ATPase activity
GO:0015675 P:nickel ion transport

References (4)

[1] “The nik operon of Escherichia coli encodes a periplasmic binding-protein-dependent transport system for nickel.”  Navarro C.et.al.   7934931
[2] “Analysis of the Escherichia coli genome. V. DNA sequence of the region from 76.0 to 81.5 minutes.”  Sofia H.J.et.al.   8041620
[3] “The complete genome sequence of Escherichia coli K-12.”  Blattner F.R.et.al.   9278503
[4] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.”  Hayashi K.et.al.   16738553

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence 
1:	MPQQIELRNI ALQAAQPLVH GVSLTLQRGR VLALVGGSGS GKSLTCAATL GILPAGVRQT 
61:	AGEILADGKP VSPCALRGIK IATIMQNPRS AFNPLHTMHT HARETCLALG KPADDATLTA 
121:	AIEAVGLENA ARVLKLYPFE MSGGMLQRMM IAMAVLCESP FIIADEPTTD LDVVAQARIL 
181:	DLLESIMQKQ APGMLLVTHD MGVVARLADD VAVMSDGKIV EQGDVETLFN APKHTVTRSL 
241:	VSAHLALYGM ELAS