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3.D.1.1.1 NADH dehydrogenase I, NuoA-N. NuoL probably comprises part of the proton pathway (Nakamaru-Ogiso et al. 2010). NuoL (ND5), NuoM (ND4) and NuoN (ND2) are all homologous to proton:sodium antiporters and may all play reoles in pumping protons using a similar mechanism (Sato et al. 2013).
Accession Number:	P33607
Protein Name:	NUOL aka B2278
Length:	613
Molecular Weight:	66438.00
Species:	Escherichia coli [83333]
Number of TMSs:	18
Location¹ / Topology² / Orientation³:	Cell inner membrane¹ / Multi-pass membrane protein²
Substrate	hydron

Structure:
RefSeq:	AP_002876.1 NP_416781.1
Entrez Gene ID:	945540
Pfam:	PF00361 PF00662
BioCyc:	EcoCyc:NUOL-MONOMER ECOL168927:B2278-MONOMER MetaCyc:NUOL-MONOMER
KEGG:	ecj:JW2273 eco:b2278
Gene Ontology GO:0005887 C:integral to plasma membrane GO:0045272 C:plasma membrane respiratory chain complex I GO:0008137 F:NADH dehydrogenase (ubiquinone) activity GO:0015453 F:oxidoreduction-driven active transmembrane ... GO:0048038 F:quinone binding GO:0009061 P:anaerobic respiration GO:0042773 P:ATP synthesis coupled electron transport
References (5) [1] “The gene locus of the proton-translocating NADH: ubiquinone oxidoreductase in Escherichia coli. Organization of the 14 genes and relationship between the derived proteins and subunits of mitochondrial complex I.” Weidner U.et.al. 7690854 [2] “Construction of a contiguous 874-kb sequence of the Escherichia coli-K12 genome corresponding to 50.0-68.8 min on the linkage map and analysis of its sequence features.” Yamamoto Y.et.al. 9205837 [3] “The complete genome sequence of Escherichia coli K-12.” Blattner F.R.et.al. 9278503 [4] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.” Hayashi K.et.al. 16738553 [5] “Global topology analysis of the Escherichia coli inner membrane proteome.” Daley D.O.et.al. 15919996
3rko

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FASTA formatted sequence

1:	MNMLALTIIL PLIGFVLLAF SRGRWSENVS AIVGVGSVGL AALVTAFIGV DFFANGEQTY 
61:	SQPLWTWMSV GDFNIGFNLV LDGLSLTMLS VVTGVGFLIH MYASWYMRGE EGYSRFFAYT 
121:	NLFIASMVVL VLADNLLLMY LGWEGVGLCS YLLIGFYYTD PKNGAAAMKA FVVTRVGDVF 
181:	LAFALFILYN ELGTLNFREM VELAPAHFAD GNNMLMWATL MLLGGAVGKS AQLPLQTWLA 
241:	DAMAGPTPVS ALIHAATMVT AGVYLIARTH GLFLMTPEVL HLVGIVGAVT LLLAGFAALV 
301:	QTDIKRVLAY STMSQIGYMF LALGVQAWDA AIFHLMTHAF FKALLFLASG SVILACHHEQ 
361:	NIFKMGGLRK SIPLVYLCFL VGGAALSALP LVTAGFFSKD EILAGAMANG HINLMVAGLV 
421:	GAFMTSLYTF RMIFIVFHGK EQIHAHAVKG VTHSLPLIVL LILSTFVGAL IVPPLQGVLP 
481:	QTTELAHGSM LTLEITSGVV AVVGILLAAW LWLGKRTLVT SIANSAPGRL LGTWWYNAWG 
541:	FDWLYDKVFV KPFLGIAWLL KRDPLNSMMN IPAVLSRFAG KGLLLSENGY LRWYVASMSI 
601:	GAVVVLALLM VLR

3.D.1.1.1
NADH dehydrogenase I, NuoA-N. NuoL probably comprises part of the proton pathway (Nakamaru-Ogiso et al. 2010). NuoL (ND5), NuoM (ND4) and NuoN (ND2) are all homologous to proton:sodium antiporters and may all play reoles in pumping protons using a similar mechanism (Sato et al. 2013).

Cross database links:

Gene Ontology

References (5)

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3.D.1.1.1NADH dehydrogenase I, NuoA-N. NuoL probably comprises part of the proton pathway (Nakamaru-Ogiso et al. 2010). NuoL (ND5), NuoM (ND4) and NuoN (ND2) are all homologous to proton:sodium antiporters and may all play reoles in pumping protons using a similar mechanism (Sato et al. 2013).

Cross database links:

Gene Ontology

References (5)

External Searches:

Analyze:

3.D.1.1.1
NADH dehydrogenase I, NuoA-N. NuoL probably comprises part of the proton pathway (Nakamaru-Ogiso et al. 2010). NuoL (ND5), NuoM (ND4) and NuoN (ND2) are all homologous to proton:sodium antiporters and may all play reoles in pumping protons using a similar mechanism (Sato et al. 2013).