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3.A.1.8.1
Molybdate porter consisting of three proteins.  Molybdate, after transport into cells by the ModABC proteins, is metabolized by the products of the mol gene(s) (Maupin-Furlow et al. 1995). The repressor of the mod operon is ModE (Grunden et al. 1996).

Accession Number:P37329
Protein Name:ModA aka B0763
Length:257
Molecular Weight:27364.00
Species:Escherichia coli [83333]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Periplasm1
Substrate Molybdate

Cross database links:

Genevestigator: P37329
EchoBASE: EB2325
EcoGene: EG12427
eggNOG: COG0725
HEGENOM: HBG566978
RefSeq: AP_001394.1    NP_415284.1   
Entrez Gene ID: 945364   
Pfam: PF01547   
BioCyc: EcoCyc:MODA-MONOMER    ECOL168927:B0763-MONOMER   
KEGG: ecj:JW0746    eco:b0763   

Gene Ontology

GO:0030288 C:outer membrane-bounded periplasmic space
GO:0015412 F:molybdate transmembrane-transporting ATPase...
GO:0015689 P:molybdate ion transport

References (7)

[1] “Regulation of the molybdate transport operon, modABCD, of Escherichia coli in response to molybdate availability.”  Rech S.et.al.   7860583
[2] “Molecular analysis of the molybdate uptake operon, modABCD, of Escherichia coli and modR, a regulatory gene.”  Walkenhorst H.M.et.al.   8564363
[3] “A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 12.7-28.0 min region on the linkage map.”  Oshima T.et.al.   8905232
[4] “The complete genome sequence of Escherichia coli K-12.”  Blattner F.R.et.al.   9278503
[5] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.”  Hayashi K.et.al.   16738553
[6] “Properties of the periplasmic ModA molybdate-binding protein of Escherichia coli.”  Rech S.et.al.   8576221
[7] “Crystal structure of the molybdate binding protein ModA.”  Hu Y.et.al.   9302996
Structure:
1AMF   1WOD   3AXF   3R26   4XXU     

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MARKWLNLFA GAALSFAVAG NALADEGKIT VFAAASLTNA MQDIATQFKK EKGVDVVSSF 
61:	ASSSTLARQI EAGAPADLFI SADQKWMDYA VDKKAIDTAT RQTLLGNSLV VVAPKASVQK 
121:	DFTIDSKTNW TSLLNGGRLA VGDPEHVPAG IYAKEALQKL GAWDTLSPKL APAEDVRGAL 
181:	ALVERNEAPL GIVYGSDAVA SKGVKVVATF PEDSHKKVEY PVAVVEGHNN ATVKAFYDYL 
241:	KGPQAAEIFK RYGFTIK