1.F.2.1.1
Yeast 8 subunit exocyst complex involved in tethering before membrane fusion between vesicles and the plasma membrane (Zárský et al. 2013). Subunits include Sec3, 1336 aas, Sec5, 971 aas, Sec6, 805 aas, Sec8, 1065 aas, Sec10, 871 aas, Sec15, 910 aas, Exo70, 623 aas and Exo84, 753 aas. Exosomes can function as nano-shuttles bearing, for example, therapeutic biomolecules (Masjedi et al. 2024).
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| Accession Number: | P38261 |
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| Protein Name: | Exocyst complex component EXO84 |
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| Length: | 753 |
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| Molecular Weight: | 85538.00 |
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| Species: | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [559292] |
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| Location1 / Topology2 / Orientation3: |
Cytoplasmic vesicle1 |
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| Substrate |
molecule |
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1: MVEFSLKKAR NNWKHVKKSA SSPAKQKTPP SPAKPKQKTK KNPYSDLKDP ATSYTLPTIN
61: ARERSRVATS MQRRLSIHNT NYAPPTLDYS MPLPDMPNMI VPNDNVDSSH NNSSFTTENE
121: SVSSKGPSNS LNLSTADLSL NDSSYNKVPA RSAMRNTVNP SGSNDPFNNS TSLRKMLANP
181: HFNAKDFVHD KLGNASAITI DKFTSNLTDL SIQVQEEVKL NINKSYNEIM TVNNDLNVAM
241: LELKRVRANI NDLNEVLDQC TKIAEKRLQL QDQIDQERQG NFNNVESHSN SPALLPPLKA
301: GQNGNLMRRD RSSVLILEKF WDTELDQLFK NVEGAQKFIN STKGRHILMN SANWMELNTT
361: TGKPLQMVQI FILNDLVLIA DKSRDKQNDF IVSQCYPLKD VTVTQEEFST KRLLFKFSNS
421: NSSLYECRDA DECSRLLDVI RKAKDDLCDI FHVEEENSKR IRESFRYLQS TQQTPGRENN
481: RSPNKNKRRS MGGSITPGRN VTGAMDQYLL QNLTLSMHSR PRSRDMSSTA QRLKFLDEGV
541: EEIDIELARL RFESAVETLL DIESQLEDLS ERISDEELML LNLISLKIEQ RREAISSKLS
601: QSILSSNEIV HLKSGTENMI KLGLPEQALD LFLQNRSNFI QDLILQIGSV DNPTNYLTQL
661: AVIRFQTIKK TVEDFQDIFK ELGAKISSIL VDWCSDEVDN HFKLIDKQLL NDEMLSPGSI
721: KSSRKQIDGL KAVGLDFVYK LDEFIKKNSD KIR