9.B.142.3.14
The glycosyltransferase complex consisting of 8 subunits, all integral membrane proteins. The high resolution 3-dimensional structure has been elucidated (Wild et al. 2018). The catalytic subunit is the STT3 protein of 718 aas and 13 TMSs. The other subunits have 1 - 6 TMSs. The function of the complex is glycosylation of newly synthesized proteins on Asn with Glc3Man9 GlcNac2.
|
| Accession Number: | P41543 |
|---|
| Protein Name: | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 |
|---|
| Length: | 476 |
|---|
| Molecular Weight: | 54072.00 |
|---|
| Species: | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [559292] |
|---|
| Number of TMSs: | 2 |
|---|
| Location1 / Topology2 / Orientation3: |
Endoplasmic reticulum membrane1 / Single-pass type I membrane protein2 |
|---|
| Substrate |
|
|---|
1: MRQVWFSWIV GLFLCFFNVS SAAQYEPPAT WENVDYKRTI DVSNAYISET IEITIKNIAS
61: EPATEYFTAF ESGIFSKVSF FSAYFTNEAT FLNSQLLANS TTAPGDDGES EIRYGIIQFP
121: NAISPQEEVS LVIKSFYNTV GIPYPEHVGM SEEQHLLWET NRLPLSAYDT KKASFTLIGS
181: SSFEEYHPPN DESLLGKANG NSFEFGPWED IPRFSSNETL AIVYSHNAPL NQVVNLRRDI
241: WLSHWASTIQ FEEYYELTNK AAKLSKGFSR LELMKQIQTQ NMRQTHFVTV LDMLLPEGAT
301: DHYFTDLVGL VSTSHAERDH FFIRPRFPIF GGWNYNFTVG WTNKLSDFLH VSSGSDEKFV
361: ASIPILNGPP DTVYDNVELS VFLPEGAEIF DIDSPVPFTN VSIETQKSYF DLNKGHVKLT
421: FSYRNLISQV ANGQVLIKYD YPKSSFFKKP LSIACYIFTA LMGVFVLKTL NMNVTN