9.A.69.1.1
The Paraquot-inducible protein (PqiABC) system of intermembrane phospholipid translocation (Nakayama and Zhang-Akiyama 2016). PqiA has 417 aas and 8 TMSs in the inner membrane; PqiB has 546 aas with several repeats that are stacked on each other to form a trans-periplasmic channel for phospholipid transport, and PqiC (ymbA) has 187 aas and possibly one N-terminal TMS is located in or on the outer membrane (Nakayama and Zhang-Akiyama 2016).
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| Accession Number: | P43671 |
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| Protein Name: | Paraquat-inducible protein B |
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| Length: | 546 |
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| Molecular Weight: | 60520.00 |
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| Species: | Escherichia coli (strain K12) [83333] |
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| Number of TMSs: | 1 |
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| Location1 / Topology2 / Orientation3: |
Cell membrane1 / Single-pass membrane protein2 |
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| Substrate |
phospholipid |
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1: MESNNGEAKI QKVKNWSPVW IFPIVTALIG AWVLFYHYSH QGPEVTLITA NAEGIEGGKT
61: TIKSRSVDVG VVESATLADD LTHVEIKARL NSGMEKLLHK DTVFWVVKPQ IGREGISGLG
121: TLLSGVYIEL QPGAKGSKMD KYDLLDSPPL APPDAKGIRV ILDSKKAGQL SPGDPVLFRG
181: YRVGSVETST FDTQKRNISY QLFINAPYDR LVTNNVRFWK DSGIAVDLTS AGMRVEMGSL
241: TTLLSGGVSF DVPEGLDLGQ PVAPKTAFVL YDDQKSIQDS LYTDHIDYLM FFKDSVRGLQ
301: PGAPVEFRGI RLGTVSKVPF FAPNMRQTFN DDYRIPVLIR IEPERLKMQL GENADVVEHL
361: GELLKRGLRG SLKTGNLVTG ALYVDLDFYP NTPAITGIRE FNGYQIIPTV SGGLAQIQQR
421: LMEALDKINK LPLNPMIEQA TSTLSESQRT MKNLQTTLDS MNKILASQSM QQLPTDMQST
481: LRELNRSMQG FQPGSAAYNK MVADMQRLDQ VLRELQPVLK TLNEKSNALV FEAKDKKDPE
541: PKRAKQ