3.A.1.115.1
Na+ efflux pump NatAB. It is induced by ethanol andby protonophores (Cheng et al. 1997). A similar system was found in the alkaliphilic Bacillus firmus OF4 species (Wei et al. 1999). The Bacillus subtilis NatK-NatR two-component system regulates expression of the natAB operon (Ogura et al. 2007).
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| Accession Number: | P46903 |
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| Protein Name: | NatA; ATP-binding transport protein (Na(+) ABC transporter) |
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| Length: | 246 |
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| Molecular Weight: | 27878.00 |
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| Species: | Bacillus subtilis [1423] |
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| Location1 / Topology2 / Orientation3: |
Cell inner membrane1 / Multi-pass membrane protein2 |
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| Substrate |
sodium(1+) |
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| RefSeq: |
NP_388157.1
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| Entrez Gene ID: |
938386
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| Pfam: |
PF00005
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| KEGG: |
bsu:BSU02750
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[1] “A two-gene ABC-type transport system that extrudes Na+ in Bacillus subtilis is induced by ethanol or protonophore.” Cheng J. et.al. 9106203
[2] “A 32 kb nucleotide sequence from the region of the lincomycin-resistance gene (22 degrees-25 degrees) of the Bacillus subtilis chromosome and identification of the site of the lin-2 mutation.” Kumano M. et.al. 9274031
[3] “The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.” Kunst F. et.al. 9384377
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1: MITLTDCSRR FQDKKKVVKA VRDVSLTIEK GEVVGILGEN GAGKTTMLRM IASLLEPSQG
61: VITVDGFDTV KQPAEVKQRI GVLFGGETGL YDRMTAKENL QYFGRLYGLN RHEIKARIED
121: LSKRFGMRDY MNRRVGGFSK GMRQKVAIAR ALIHDPDIIL FDEPTTGLDI TSSNIFREFI
181: QQLKREQKTI LFSSHIMEEV QALCDSVIMI HSGEVIYRGA LESLYESERS EDLNYIFMSK
241: LVRGIS