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9.A.50.1.1 The tRNA nuclear export machinery, t-Exporter. Includes UTP8, a tRNA-binding protein, Los1 and Msn5/ two tRNA export receptors (Strub et al., 2007). Phosphate-dependent nuclear export via a non-classical NES class recognized by exportin Msn5 has been reported (Fung et al. 2025).
Accession Number:	P52918
Protein Name:	Msn5
Length:	1224
Molecular Weight:	142118.00
Species:	Saccharomyces cerevisiae [4932]
Location¹ / Topology² / Orientation³:	Nucleus¹
Substrate	protein, transfer RNA

DIP:	DIP-1459N
RefSeq:	NP_010622.1
Entrez Gene ID:	851935
KEGG:	sce:YDR335W
Gene Ontology GO:0005634 C:nucleus GO:0008262 F:importin-alpha export receptor activity GO:0006611 P:protein export from nucleus GO:0071528 P:tRNA re-export from nucleus
References (2) [1] “The nucleotide sequence of Saccharomyces cerevisiae chromosome IV.” Jacq C.et.al. 9169867 [2] “Global analysis of protein expression in yeast.” Ghaemmaghami S.et.al. 14562106

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MDSTGASQIV SALDVIYSPK SNNSQRQEAQ KFLDEVKLCS ESPFWGYEIA LQNPTNSILK 
61:	YFGLGLLDHA VKKNWNDYDE GKRVALRKWV MELNFGVQDY DTRYIKEKLA TLWVEVAKRT 
121:	WGEALKQTNP TEEQLLTSWV DMDNNLFELW NINQSSRELA LIIFRILFED VFLLDDLIVL 
181:	KRMTVIQPLC VMIVCPIEVF AIKYKFSDKW TKFKANEEGW FSVWIPELNN ALQQNNSEYI 
241:	IRLLETLKTC LNWPLTEVIV RNDVLSSLLT CLSSNIPRAQ SMALDSIHIL LTRPYSNESH 
301:	YQMTIDRVFD NMDLLDSVYE SLLFDPTDDI DETKYPIIKK FVDMISCLYV CVPKIKETNG 
361:	QIQKYFKLVL KTTYNPSLIV SGLTLDLWCT CLRNDEYLPK LEKYVIPDLL QFAADALVYY 
421:	EQIDGHISKK FAEIDFQSKS EFQTFCSTYR KRIRDIIRLI SCVELDLTYD WLNNRLNNYF 
481:	SSPFGQQVLS STFLDHKLEP YLGALSQYMI VECFINGCIR WKIWYPTGDD YDEKLDSILQ 
541:	KLEILSNQLI ALNLREPLLL KKQIQNFALF LTMLKDNVLF TLLEKIITSA TMDYPEINLE 
601:	ERGAESDAVR DLRYACGIEL NRMALLMPES LKKIYPDLES VIARIMPNLS YHEKISFKSF 
661:	LLIIVLKSSL DMKEERFAAI VDPELLAWSD KTTVVGLSDL HWFMERLGIV QIAEYFQRRD 
721:	IDENSDLLSI PIDDEGKELK SELTKRWQSL FPVRATRMFI HYSMQSIKTD EEFKMLQDLW 
781:	RPRIVPILPY ITRLLYQLQS YHDPDNWKGL PTVVQSFVKY STIERFWEAG ASNKSKDEFI 
841:	DEHMKAMQTL RDFADSVGHI IRYTREYTLL VLSAISSLGS VFYLLDESPD LLLNSIAIFK 
901:	PGSNEISPGV STHGWKHIMN IAIRPILKGC PKDCLGKFMP AFLPKLFEIL DLLLCQKWSS 
961:	HMNDMDMNPV PTDDDQMTEE ILEENLLRQL TTVVVRIVID CVGQGNANPN SAKSRLNNHQ 
1021:	MEMRKIIFND LNTLAPFLKL LNHLISFKDT KCSFNSILVM KCCLTSVLNQ NNTVDEYFTF 
1081:	EVMKNLLLNV LCNSAFKDSF HEALYAFTVI FLTLCKEYPS ARAFLFEISN GYNIDELYRN 
1141:	LRSVDEYKTQ RALMIDFIDW VKSTSGKEDG NVDHAGDERK RQEKREAILK KANERLIKKN 
1201:	KENGDMLDDP NIEDGAVGNL FDDN

9.A.50.1.1
The tRNA nuclear export machinery, t-Exporter. Includes UTP8, a tRNA-binding protein, Los1 and Msn5/ two tRNA export receptors (Strub et al., 2007). Phosphate-dependent nuclear export via a non-classical NES class recognized by exportin Msn5 has been reported (Fung et al. 2025).

Cross database links:

Gene Ontology

References (2)

External Searches:

Analyze:

9.A.50.1.1The tRNA nuclear export machinery, t-Exporter. Includes UTP8, a tRNA-binding protein, Los1 and Msn5/ two tRNA export receptors (Strub et al., 2007). Phosphate-dependent nuclear export via a non-classical NES class recognized by exportin Msn5 has been reported (Fung et al. 2025).

Cross database links:

Gene Ontology

References (2)

External Searches:

Analyze:

9.A.50.1.1
The tRNA nuclear export machinery, t-Exporter. Includes UTP8, a tRNA-binding protein, Los1 and Msn5/ two tRNA export receptors (Strub et al., 2007). Phosphate-dependent nuclear export via a non-classical NES class recognized by exportin Msn5 has been reported (Fung et al. 2025).