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3.A.1.143.1
The exoprotein (including α-amylase) secretion system, EcsAB(C) (Leskelä et al., 1999). Also may play roles in sporulation, competence (Leskelä et al., 1996) and transformation using purified DNA (Takeno et al., 2011). An involvement of EcsC in transport is not established, but it is similar in sequence to the C-terminus of the P-type ATPase, 3.A.3.31.2.

Accession Number:P55340
Protein Name:Protein ecsB
Length:408
Molecular Weight:47300.00
Species:Bacillus subtilis (strain 168) [224308]
Number of TMSs:10
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate proteins

Cross database links:

eggNOG: COG4473
HEGENOM: HOG000060842
Entrez Gene ID: 939298   
Pfam: PF05975   
KEGG: bsu:BSU10050   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0030420 P:establishment of competence for transformation
GO:0030435 P:sporulation resulting in formation of a cellular spore
GO:0006810 P:transport

References (4)

[1] “Molecular analysis of an operon in Bacillus subtilis encoding a novel ABC transporter with a role in exoprotein production, sporulation and competence.”  Leskela S.et.al.   8581172
[2] “The 172 kb prkA-addAB region from 83 degrees to 97 degrees of the Bacillus subtilis chromosome contains several dysfunctional genes, the glyB marker, many genes encoding transporter proteins, and the ubiquitous hit gene.”  Noback M.A.et.al.   9579061
[3] “The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.”  Kunst F.et.al.   9384377
[4] “Genes involved in formation of structured multicellular communities by Bacillus subtilis.”  Branda S.S.et.al.   15175311

External Searches:

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  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MNNMLDIWQS RLQEHIKETR TYMKYMLNDH LVIVLIFFLA GAASWYSKWI RDIPAHFPSF 
61:	WVMAVLFSLV LTSSYVRTLL KEADLVFLLP LEAKMEPYLK QAFVYSYVSQ LFPLIALSIV 
121:	AMPLYFAVTP GASLVSYAAV FVQLLLLKAW NQVMEWRTTF QNDRSMKRMD VIIRFAANTL 
181:	VLYFVFQSVY MYALLVYVIM AVLYLYMSSA AKRKTFKWES HIESELRRKQ RFYRIANLFT 
241:	DVPHLRKQAK RRAYLDFLLR LVPFEQRKTF AYMFTRAFLR SSDYLGILVR LTIVFALIIM 
301:	YVSASPLIAA VLTVFAIFIT GIQLLPLFGH FDHLALQELY PVQKETKLKS YFSLLKTALS 
361:	IQALLMSVAS AYAAGLTGFL YALIGSAVLI FVVLPAYMTT RLKKHGKL