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3.A.1.5.26 The glutathione transporter, OppA (Dasgupta et al., 2010). OppA binds glutathione and the nanopeptide, bradykinin. Also regulates cytokine release, apoptosis and the innate immune response of macrophages infected with M. tuberculosis (Dasgupta et al., 2010).
Accession Number:	P66966
Protein Name:	Putative peptide transport permease protein Rv1283c/MT1320
Length:	325
Molecular Weight:	35083.00
Species:	Mycobacterium tuberculosis [1773]
Number of TMSs:	6
Location¹ / Topology² / Orientation³:	Cell membrane¹ / Multi-pass membrane protein²
Substrate	glutathione, bradykinin

Entrez Gene ID:	886981 924752
Pfam:	PF00528
KEGG:	mtc:MT1320 mtu:Rv1283c
Gene Ontology GO:0016021 C:integral to membrane GO:0005886 C:plasma membrane GO:0005215 F:transporter activity GO:0015833 P:peptide transport GO:0015031 P:protein transport
References (2) [1] “Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.” Cole S.T.et.al. 9634230 [2] “Whole-genome comparison of Mycobacterium tuberculosis clinical and laboratory strains.” Fleischmann R.D.et.al. 12218036

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MTRYLARRLL NYLVLLALAS FLTYCLTSLA FSPLESLMQR SPRPPQAVID AKAHDLGLDR 
61:	PILARYANWV SHAVRGDFGT TITGQPVGTE LGRRIGVSLR LLVVGSVFGT VAGVVIGAWG 
121:	AIRQYRLSDR VMTTLALLVL STPTFVVANL LILGALRVNW AVGIQLFDYT GETSPGVAGG 
181:	VWDRLGDRLQ HLILPSLTLA LAAAAGFSRY QRNAMLDVLG QDFIRTARAK GLTRRRALLK 
241:	HGLRTALIPM ATLFAYGVAG LVTGAVFVEK IFGWHGMGEW MVRGISTQDT NIVAAITVFS 
301:	GAVVLLAGLL SDVIYAALDP RVRVS

3.A.1.5.26
The glutathione transporter, OppA (Dasgupta et al., 2010). OppA binds glutathione and the nanopeptide, bradykinin. Also regulates cytokine release, apoptosis and the innate immune response of macrophages infected with M. tuberculosis (Dasgupta et al., 2010).

Cross database links:

Gene Ontology

References (2)

External Searches:

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3.A.1.5.26The glutathione transporter, OppA (Dasgupta et al., 2010). OppA binds glutathione and the nanopeptide, bradykinin. Also regulates cytokine release, apoptosis and the innate immune response of macrophages infected with M. tuberculosis (Dasgupta et al., 2010).

Cross database links:

Gene Ontology

References (2)

External Searches:

Analyze:

3.A.1.5.26
The glutathione transporter, OppA (Dasgupta et al., 2010). OppA binds glutathione and the nanopeptide, bradykinin. Also regulates cytokine release, apoptosis and the innate immune response of macrophages infected with M. tuberculosis (Dasgupta et al., 2010).