3.A.1.5.41
Oligopeptide transporter, OppABCDF/MppA/YgiS. MppA is a murein peptide receptor, and YgiS is a bile acid (e.g., cholate, deoxycholate) receptor that may use the Opp system for uptake. YgiS mRNA is degraded by the toxin, MgsR, which is regulated by the antitoxin, MgsA, and this loss of the mRNA protects the cell against bile acid stress (Kwan et al. 2015). oppA translation is activated by MicF through a mechanism of
action involving facilitated access to a translation-enhancing region in
oppA 5'UTR. MicF activation of oppA translation depends on cross-regulation by negative trans-acting effectors, the GcvB sRNA and the RNA chaperone protein Hfq (Carrier et al. 2023).
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| Accession Number: | P76027 |
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| Protein Name: | Oligopeptide transport ATP-binding protein OppD |
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| Length: | 337 |
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| Molecular Weight: | 37188.00 |
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| Species: | Escherichia coli (strain K12) [83333] |
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| Location1 / Topology2 / Orientation3: |
Cell inner membrane1 / Peripheral membrane protein2 |
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| Substrate |
oligopeptide |
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1: MSVIETATVP LAQQQADALL NVKDLRVTFS TPDGDVTAVN DLNFSLRAGE TLGIVGESGS
61: GKSQTAFALM GLLAANGRIG GSATFNGREI LNLPEHELNK LRAEQISMIF QDPMTSLNPY
121: MRVGEQLMEV LMLHKNMSKA EAFEESVRML DAVKMPEARK RMKMYPHEFS GGMRQRVMIA
181: MALLCRPKLL IADEPTTALD VTVQAQIMTL LNELKREFNT AIIMITHDLV VVAGICDKVL
241: VMYAGRTMEY GNARDVFYQP VHPYSIGLLN AVPRLDAEGE TMLTIPGNPP NLLRLPKGCP
301: FQPRCPHAME ICSSAPPLEE FTPGRLRACF KPVEELL