Search TCDB: (?)
TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


3.C.1.1.1
Na+-transporting tetrahydromethanopterin S-methyltransferase (NMM), MtrABCDEFGH (Harms et al. 1995).  MtrA shows a short region of sequence similarity with MtrF; MtrB shows a shortregion of sezquence similarity with MtrG (all in their C-terminal TMSs). However, MtrC, D, E and H do not show noticable sequence similarity with other members of this system.

Accession Number:P80185
Protein Name:MtrC
Length:267
Molecular Weight:27117.00
Species:Methanobacterium thermoautotrophicum (strain Marburg / DSM 2133) [79929]
Number of TMSs:8
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate sodium(1+)

Cross database links:

Pfam: PF04211   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0030269 F:tetrahydromethanopterin S-methyltransferase...
GO:0015948 P:methanogenesis
GO:0006730 P:one-carbon metabolic process

References (3)

[1] “Cloning, sequencing and immunological characterization of the corrinoid-containing subunit of the N5-methyltetrahydromethanopterin: coenzyme-M methyltransferase from Methanobacterium thermoautotrophicum.”  Stupperich E.et.al.   8223548
[2] “Purification and properties of N5-methyltetrahydromethanopterin:coenzyme M methyltransferase from Methanobacterium thermoautotrophicum.”  Gaertner P.et.al.   8477726
[3] “The energy conserving N5-methyltetrahydromethanopterin:coenzyme M methyltransferase complex from Methanobacterium thermoautotrophicum is composed of eight different subunits.”  Harms U.et.al.   7737157

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence 
1:	MSVAAGGPAG AAIPESRLMA LGILGGLAGI YASAVNPVIG PVLASLGAVC AIVWGADAIR 
61:	RVASYGLGTG VPSIGYMSVS IGIVGVVAGL ASVFVVPAIA VPVVALILAM ILGVVVAVLG 
121:	KKIVKMKIPI LEKCTAEISG AAALSVLGFS AAIAGSYTLQ TMLTSVITTG FIGLLFILNT 
181:	MAIQHPFNAC LGPNENQTRT LKLAASTGFI SMAIVGLLGI GLNPSWWLVS LIGALCWIVA 
241:	FRAFVSASFE EAASVKWSGL WPKEEEH