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2.A.6.2.16
Multidrug efflux pump, MexEF-OprN (exports fluoroquinolones, chloramphenicol, biocides, and xenobiotics; functions with MexE (MFP) and OprN (OMF)) as noted above (Kohler et al., 1997; Poole, 2008; Lorusso et al. 2022). The P. putida orthologue also exports solvents such as farnesyl hexanoate (Dunlop et al. 2011). MexAB-OprM is one of four primary drug exporters in P. aeruginosa (Lorusso et al. 2022).

Accession Number:P95421
Protein Name:HlyD_D23 domain-containing protein
Length:414
Molecular Weight:44987.00
Species:Pseudomonas aeruginosa [287]
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Lipid-anchor2
Substrate fluoroquinolone antibiotic, chloramphenicol, acrolein

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FASTA formatted sequence 
1:	MEQSSHFSWR YPLALAAVLV LSACGKAPET TQGMAAPKVS VAEVIEQPLN EWDEFTGRLE 
61:	APESVELRPR VSGYIDRVAF HEGALVKKGD LLFQIDPRPF EAEVKRLEAQ LQQARAAQAR 
121:	SVNEAQRGER LRASNAISAE LADARTTAAQ EAKAAVAATQ AQLDAARLNL SFTRITAPID 
181:	GRVSRAEVTA GNLVNSGETC SPPLVSTDKV YAYFDADERV FLKYVELARQ AGRDTRSESP 
241:	VYLGLSSEDG NPHLGRLDFL DNQVNPRTGT IRGRAVFDNA KGEFTPGLYV RLKLVGSKTY 
301:	AATLIKDEAV GTDLGKKFVL VLDGDNKTVY RTVEMGPKLE GLRIVRSGLS KGDRIVVNGL 
361:	QRVRPGMQVD PQKVEMASAD TLATLARLRQ SVGDSEPPKV AASKDNATRN EPRG