9.B.142.3.14 The glycosyltransferase complex consisting of 8 subunits, all integral membrane proteins. The high resolution 3-dimensional structure has been elucidated (Wild et al. 2018). The catalytic subunit is the STT3 protein of 718 aas and 13 TMSs. The other subunits have 1 - 6 TMSs. The function of the complex is glycosylation of newly synthesized proteins on Asn with Glc3Man9 GlcNac2.
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Accession Number: | Q02795 |
Protein Name: | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit SWP1 |
Length: | 286 |
Molecular Weight: | 31653.00 |
Species: | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [559292] |
Number of TMSs: | 4 |
Location1 / Topology2 / Orientation3: |
Endoplasmic reticulum membrane1 / Multi-pass membrane protein2 |
Substrate |
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1: MQFFKTLAAL VSCISFVLAY VAQDVHVSFP STAGKSRVMI GKVEPRIGID ETVPTTITVE
61: DPNEVIQVNF AIESTNKPFQ NTLLIGLPNK NLEMAFEPEI KDNGKLSMYK YRIDLAKLDA
121: ALLQEASRSP EPIKATLILA SSTAKPKENL FREILQLNLN FDVDHSDSSL VDKFGIKPEI
181: HHIFHAEPKR VAKPIAVIFV LIIFITILSL IVTWLNSCAA AFNNIPTGVT AVYFLGFIAT
241: IVGFEVIFAR YYLGTSIFET LFSSLYLGAP GLLTSTKFLR SFGQTI