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3.A.20.1.5
The peroxisome complex for protein import into peroxisomes (Kiel et al. 2006).

Accession Number:Q07418
Protein Name:Pex19 aka Peroxin-19
Length:342
Molecular Weight:38706.00
Species:Saccharomyces cerevisiae (Baker's yeast) [4932]
Location1 / Topology2 / Orientation3: Cytoplasm1 / Lipid-anchor2 / Cytoplasmic side3
Substrate protein polypeptide chain

Cross database links:

DIP: DIP-1563N
RefSeq: NP_010218.2   
Entrez Gene ID: 851494   
Pfam: PF04614   
KEGG: sce:YDL065C   

Gene Ontology

GO:0005829 C:cytosol
GO:0005789 C:endoplasmic reticulum membrane
GO:0005778 C:peroxisomal membrane
GO:0033328 F:peroxisome membrane targeting sequence binding
GO:0005515 F:protein binding
GO:0032527 P:protein exit from endoplasmic reticulum
GO:0045046 P:protein import into peroxisome membrane
GO:0050821 P:protein stabilization

References (17)

[1] “Pex19p, a farnesylated protein essential for peroxisome biogenesis.”  Goette K.et.al.   9418908
[2] “The nucleotide sequence of Saccharomyces cerevisiae chromosome IV.”  Jacq C.et.al.   9169867
[3] “Saccharomyces cerevisiae Pex3p and Pex19p are required for proper localization and stability of peroxisomal membrane proteins.”  Hettema E.H.et.al.   10637226
[4] “Pex10p links the ubiquitin conjugating enzyme Pex4p to the protein import machinery of the peroxisome.”  Eckert J.H.et.al.   12876220
[5] “Sequencing and comparison of yeast species to identify genes and regulatory elements.”  Kellis M.et.al.   12748633
[6] “Global analysis of protein localization in budding yeast.”  Huh W.-K.et.al.   14562095
[7] “Global analysis of protein expression in yeast.”  Ghaemmaghami S.et.al.   14562106
[8] “Finding functional features in Saccharomyces genomes by phylogenetic footprinting.”  Cliften P.F.et.al.   12775844
[9] “Peroxisomal membrane proteins contain common Pex19p-binding sites that are an integral part of their targeting signals.”  Rottensteiner H.et.al.   15133130
[10] “Contribution of the endoplasmic reticulum to peroxisome formation.”  Hoepfner D.et.al.   16009135
[11] “Pex3p initiates the formation of a preperoxisomal compartment from a subdomain of the endoplasmic reticulum in Saccharomyces cerevisiae.”  Tam Y.Y.C.et.al.   16087670
[12] “Farnesylation of Pex19p is not essential for peroxisome biogenesis in yeast and mammalian cells.”  Vastiau I.M.K.et.al.   16791427
[13] “The dynamin-like protein Vps1p of the yeast Saccharomyces cerevisiae associates with peroxisomes in a Pex19p-dependent manner.”  Vizeacoumar F.J.et.al.   16520372
[14] “Pex19p binds Pex30p and Pex32p at regions required for their peroxisomal localization but separate from their peroxisomal targeting signals.”  Vizeacoumar F.J.et.al.   16551610
[15] “Pex19p-dependent targeting of Pex17p, a peripheral component of the peroxisomal protein import machinery.”  Girzalsky W.et.al.   16679311
[16] “Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae.”  Li X.et.al.   17330950
[17] “A multidimensional chromatography technology for in-depth phosphoproteome analysis.”  Albuquerque C.P.et.al.   18407956

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MNENEYDNFD DLDDLLDEDP TKLDEAEPDD VQAKGSVYND SENKEKNAES KDSDGVQVAN 
61:	ESEEDPELKE MMVDLQNEFA NLMKNNGNEN NVKTEDFNKL ISALEEAAKV PHQQMEQGCS 
121:	SLKSNSTDKG TVNGSNPGFK NIVSNTLDRL KENGNKVDTS LAEETKESQR SGQNNNIDDI 
181:	LSQLLDQMVA SGGKESAENQ FDLKDGEMDD AITKILDQMT SKEVLYEPMK EMRSEFGVWF 
241:	QENGENEEHK EKIGTYKRQF NIVDEIVNIY ELKDYDELKH KDRVTELLDE LEQLGDSPIR 
301:	SANSPLKHGN EEEELMKMLE IDGNDPNLGN LDKELTDGCK QQ