8.A.132.1.13 Interleukin-10 receptor, subunits alpha/beta. The alpha subunit has 578 aas with 2 TMSs, one N-terminal and the other at ~ residue 245 and the beta subunit is of 325 aas, with 2 TMSs, one N-terminal and the other at ~ residue 230. A cryoEM structure is available (Cai et al. 2022).
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Accession Number: | Q08334 |
Protein Name: | Interleukin-10 receptor subunit beta |
Length: | 325 |
Molecular Weight: | 36995.00 |
Species: | Homo sapiens (Human) [9606] |
Number of TMSs: | 1 |
Location1 / Topology2 / Orientation3: |
Membrane1 / Single-pass type I membrane protein2 |
Substrate |
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1: MAWSLGSWLG GCLLVSALGM VPPPENVRMN SVNFKNILQW ESPAFAKGNL TFTAQYLSYR
61: IFQDKCMNTT LTECDFSSLS KYGDHTLRVR AEFADEHSDW VNITFCPVDD TIIGPPGMQV
121: EVLADSLHMR FLAPKIENEY ETWTMKNVYN SWTYNVQYWK NGTDEKFQIT PQYDFEVLRN
181: LEPWTTYCVQ VRGFLPDRNK AGEWSEPVCE QTTHDETVPS WMVAVILMAS VFMVCLALLG
241: CFALLWCVYK KTKYAFSPRN SLPQHLKEFL GHPHHNTLLF FSFPLSDEND VFDKLSVIAE
301: DSESGKQNPG DSCSLGTPPG QGPQS