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3.A.1.27.4 The cholesterol uptake porter (Mohn et al., 2008). Takes up cholesterol, 5-α-cholestanol, 5-α-cholestanone, β-sitosterol, etc. (It is not established that all of these proteins comprise the system or that other gene products are not involved.)
Accession Number:	Q0S7K2
Protein Name:	MCE family protein
Length:	391
Molecular Weight:	41275.00
Species:	rhodococcus sp. (strain rha1) [101510]
Number of TMSs:	1
Location¹ / Topology² / Orientation³:	Cell inner membrane¹ / Peripheral membrane protein² / Cytoplasmic side³
Substrate	cholesterol

RefSeq:	YP_704642.1
Entrez Gene ID:	4222249
Pfam:	PF02470
BioCyc:	RSP101510:RHA1_RO04698-MONOMER
KEGG:	rha:RHA1_ro0469
References (1) [1] “The complete genome of Rhodococcus sp. RHA1 provides insights into a catabolic powerhouse.” McLeod M.P.et.al. 17030794

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MTDSGGKKKL AALVLVVSLL AIIGVSLAMF NGTFSETTPV TVTSDRSGLV MEPDAKVKLL 
61:	GVEVGRVGSI EHVTDGAELK LAMYPDMMSL IPSNATVEIK STTVFGAKYV NFVMPDNPSS 
121:	TPLQAGDVIA SDNVTVEFNT VFQHLSDVLA QVQPEKLNAT LGAISSALRG RGEELGALLE 
181:	QSDSYLAKMN PSLPQLQEDF AKAAQVTDVY ADTAPDLLRV LDNATATSGT VVDEQDNLDA 
241:	VLLNVTGLAD TANTVLTENE QNLNSSLDLL LPTTDLLAEY SPEISCFIVG LNNVIPLAEQ 
301:	LIGGNQPGIA LSASFMYGQE PYTYPKDLPK VNATGGPNCH GLPNPDLSKH ANFVVADTGT 
361:	VPFVPSTEVQ VHLPKVFQLL FAGVYPGQGG Q

3.A.1.27.4
The cholesterol uptake porter (Mohn et al., 2008). Takes up cholesterol, 5-α-cholestanol, 5-α-cholestanone, β-sitosterol, etc. (It is not established that all of these proteins comprise the system or that other gene products are not involved.)

Cross database links:

References (1)

External Searches:

Analyze:

3.A.1.27.4The cholesterol uptake porter (Mohn et al., 2008). Takes up cholesterol, 5-α-cholestanol, 5-α-cholestanone, β-sitosterol, etc. (It is not established that all of these proteins comprise the system or that other gene products are not involved.)

Cross database links:

References (1)

External Searches:

Analyze:

3.A.1.27.4
The cholesterol uptake porter (Mohn et al., 2008). Takes up cholesterol, 5-α-cholestanol, 5-α-cholestanone, β-sitosterol, etc. (It is not established that all of these proteins comprise the system or that other gene products are not involved.)