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8.A.132.1.13 Interleukin-10 receptor, subunits alpha/beta. The alpha subunit has 578 aas with 2 TMSs, one N-terminal and the other at ~ residue 245 and the beta subunit is of 325 aas, with 2 TMSs, one N-terminal and the other at ~ residue 230. A cryoEM structure is available (Cai et al. 2022).
Accession Number:	Q13651
Protein Name:	Interleukin-10 receptor subunit alpha
Length:	578
Molecular Weight:	63003.00
Species:	Homo sapiens (Human) [9606]
Number of TMSs:	1
Location¹ / Topology² / Orientation³:	Cell membrane¹ / Single-pass type I membrane protein²
Substrate

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MLPCLVVLLA ALLSLRLGSD AHGTELPSPP SVWFEAEFFH HILHWTPIPN QSESTCYEVA 
61:	LLRYGIESWN SISNCSQTLS YDLTAVTLDL YHSNGYRARV RAVDGSRHSN WTVTNTRFSV 
121:	DEVTLTVGSV NLEIHNGFIL GKIQLPRPKM APANDTYESI FSHFREYEIA IRKVPGNFTF 
181:	THKKVKHENF SLLTSGEVGE FCVQVKPSVA SRSNKGMWSK EECISLTRQY FTVTNVIIFF 
241:	AFVLLLSGAL AYCLALQLYV RRRKKLPSVL LFKKPSPFIF ISQRPSPETQ DTIHPLDEEA 
301:	FLKVSPELKN LDLHGSTDSG FGSTKPSLQT EEPQFLLPDP HPQADRTLGN REPPVLGDSC 
361:	SSGSSNSTDS GICLQEPSLS PSTGPTWEQQ VGSNSRGQDD SGIDLVQNSE GRAGDTQGGS 
421:	ALGHHSPPEP EVPGEEDPAA VAFQGYLRQT RCAEEKATKT GCLEEESPLT DGLGPKFGRC 
481:	LVDEAGLHPP ALAKGYLKQD PLEMTLASSG APTGQWNQPT EEWSLLALSS CSDLGISDWS 
541:	FAHDLAPLGC VAAPGGLLGS FNSDLVTLPL ISSLQSSE

8.A.132.1.13
Interleukin-10 receptor, subunits alpha/beta. The alpha subunit has 578 aas with 2 TMSs, one N-terminal and the other at ~ residue 245 and the beta subunit is of 325 aas, with 2 TMSs, one N-terminal and the other at ~ residue 230. A cryoEM structure is available (Cai et al. 2022).

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8.A.132.1.13Interleukin-10 receptor, subunits alpha/beta. The alpha subunit has 578 aas with 2 TMSs, one N-terminal and the other at ~ residue 245 and the beta subunit is of 325 aas, with 2 TMSs, one N-terminal and the other at ~ residue 230. A cryoEM structure is available (Cai et al. 2022).

Cross database links:

External Searches:

Analyze:

8.A.132.1.13
Interleukin-10 receptor, subunits alpha/beta. The alpha subunit has 578 aas with 2 TMSs, one N-terminal and the other at ~ residue 245 and the beta subunit is of 325 aas, with 2 TMSs, one N-terminal and the other at ~ residue 230. A cryoEM structure is available (Cai et al. 2022).