TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


3.A.7.14.2
Conjugation system, IntP/TcpA-J (Bannam et al., 2008; Teng et al., 2008). TcpA but not TcpB is essential for transfer of the conjugative plasmid pCW3 (Parsons et al., 2007). TcpA interacts with other pCW3-encoded proteins to form an essential part of the conjugation complex (Steen et al., 2009).

Accession Number:Q15HV3
Protein Name:TcpA
Length:532
Molecular Weight:61127.00
Species:Clostridium perfringens [1502]
Number of TMSs:4
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate deoxyribonucleic acid

Cross database links:

Pfam: PF01580   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005622 C:intracellular
GO:0005524 F:ATP binding
GO:0003677 F:DNA binding
GO:0017111 F:nucleoside-triphosphatase activity
GO:0008134 F:transcription factor binding
GO:0007049 P:cell cycle
GO:0051301 P:cell division
GO:0007059 P:chromosome segregation
GO:0006355 P:regulation of transcription, DNA-dependent

References (2)

[1] “Functional identification of conjugation and replication regions of the tetracycline resistance plasmid pCW3 from Clostridium perfringens.”  Bannam T.L.et.al.   16788202
[2] “Functional identification of conjugation and replication regions of the tetracycline resistance plasmid pCW3 from Clostridium perfringens.”  Bannam T.L.et.al.   16788202

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence
1:	MIFLSSDWEK KVNQEIENGA NAIINEIANV LRIFFFRVGL GFKKSWKNKK LFIGFFLSFL 
61:	IPIAARIKSD YFLVDTKFYF KIIYFSTFIA PLFYMAIISF VNRKGDKVEE EFKKAFEEMG 
121:	FIDISGNAPK LINIKHDELT GIDQYFFKTF IPLDDWQPKA RLMESRLNKT IFEIIQGIDK 
181:	QTVQMNALEG SVKVSDKLLW SNDLIREEGV LNFGKSISSE IKIDLDEQPH VLVAGQTGSG 
241:	KSVLMRCLLW QVYCQGADVY MIDFKAGVEF GLDYEKIGKV MTEVDETLKL LETLIVENTD 
301:	RLKKFREAKV KNLKEYNKKF KTHLKRKVVF IDEMAQLMDS SGVDKETKAK LEKISYCIAT 
361:	LARTARASGI NLVLGAQRPD ANVMNGQIKN NVTVRVCGRF ADGPVSEIVL GNNKAKKLPE 
421:	IKGRFLFKVD ANTIEFQAYY FNDDKDFKPE QVERQKSQYE FISIKSSDDD LIIEDAPVEN 
481:	ISVVENKTFD DIKQEIDVNK DLKQEKQDVN KELKSKNKTD ILSSKDWDAS NF