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3.D.1.6.2
The fungal H+ translocating NADH dehydrogenase (NDH) complex (38 subunits; 35 included here) (Cardol et al., 2004).  The high resolution (3.6 - 3.9 Å) structure of the mitochondrial Yarrowia lipolytica enzyme, showing all central subunits that execute the bioenergetic functions, has been solved (see discussion for TC# 3.A.1 and Zickermann et al. 2015). The subunit inventory of mitochondrial complex I from the obligate aerobic yeast Yarrowia lipolytica involved a total of 37 subunits (Abdrakhmanova et al. 2004).

Accession Number:Q35140
Protein Name:ND2 (66) (NuoN)
Length:583
Molecular Weight:65838.00
Species:Neurospora crassa [5141]
Number of TMSs:13
Location1 / Topology2 / Orientation3: Mitochondrion inner membrane1 / Multi-pass membrane protein2
Substrate hydron

Cross database links:

Pfam: PF00361   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005743 C:mitochondrial inner membrane
GO:0070469 C:respiratory chain
GO:0008137 F:NADH dehydrogenase (ubiquinone) activity
GO:0042773 P:ATP synthesis coupled electron transport
GO:0006810 P:transport

References (1)

[1] “The E35 stopper mutant of Neurospora crassa: precise localization of deletion endpoints in mitochondrial DNA and evidence that the deleted DNA codes for a subunit of NADH dehydrogenase.”  de Vries H.et.al.   3011426

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence 
1:	MIIMTILSLL LSNAVTLRRD ISILFNRIVI IALIYCILHD TMSLSIISKG VGLHGGLLHI 
61:	TNITQVFQIF IFLISILILQ LTSFDPIKKF YIMRHPRFIN KWPRAIGYSI PLSSIQAVLK 
121:	DYLFKIQGFN KEHLKIIEYP LILLFVICGA VFLMSTNDLV SIFLSIELQS YGLHTSSTIY 
181:	RNSELSTTGG LIYFLLGGFS SCFILLGASL LYANSGTTSL DGLYIINSIS DVNDNMTSWY 
241:	KSYYLNFSLL IFSVGFLFKV SAAPFHFWSP DVYDAIPTIV TTFVAIIAKI SIFILLLELV 
301:	YHTNNYLSEF SWIYGLLVSS FLSLIIGTVV GLTQFRIKRL LAYSTISHLG FILLALSVFT 
361:	QSVESTQAFI FYLIQYSFSN LNVFIILITI GFSLYGYVWN NKEYKNLLDI NNSPVQLISQ 
421:	LKGYFYLNPL LSLSLAITIF SFAGIPPLVG FFAKQMVLSA ALDNGYIFLS LIAILTSVVG 
481:	AVYYLNIIKE IFFYSPRHKL KTVDVENTWP FPVKRDLKLN DSNAFSISYD RYTVSSPLSS 
541:	GYTISSPFSI TISIITIVIL LFIFMNKEWL SMGTIMVQVL FST