3.A.7.3.1 Pertussis toxin exporter. For consideration of the requirements for assembly, see Verma and Burns, 2007.
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Accession Number: | Q45390 |
Protein Name: | PtlA |
Length: | 102 |
Molecular Weight: | 10813.00 |
Species: | Bordetella pertussis [520] |
Number of TMSs: | 3 |
Location1 / Topology2 / Orientation3: |
Cell membrane1 / Multi-pass membrane protein2 |
Substrate |
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---|
RefSeq: |
NP_882287.1
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Entrez Gene ID: |
2665409
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Pfam: |
PF04956
|
BioCyc: |
BPER257313:BP3788-MONOMER
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KEGG: |
bpe:BP3788
|
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[1] “Cloning and sequencing of the pertussis toxin genes: operon structure and gene duplication.” Nicosia A. et.al. 2873570
[2] “Molecular characterization of an operon required for pertussis toxin secretion.” Weiss A.A. et.al. 8464913
[3] “Comparative analysis of the genome sequences of Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica.” Parkhill J. et.al. 12910271
[4] “Synergistic binding of RNA polymerase and BvgA phosphate to the pertussis toxin promoter of Bordetella pertussis.” Boucher P.E. et.al. 7592424
[5] “The pertussis toxin liberation genes of Bordetella pertussis are transcriptionally linked to the pertussis toxin operon.” Ricci S. et.al. 8606119
[6] “Mutants in the ptlA-H genes of Bordetella pertussis are deficient for pertussis toxin secretion.” Craig-Mylius K.A. et.al. 10518754
[7] “Analysis of subassemblies of pertussis toxin subunits in vivo and their interaction with the ptl transport apparatus.” Burns D.L. et.al. 15322034
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1: MNPLKDLRAS LPRLAFMAAC TLLSATLPDL AQAGGGLQRV NHFMASIVVV LRGASVATVT
61: IAIIWAGYKL LFRHADVLDV VRVVLAGLLI GASAEIARYL LT