Search TCDB: (?)
TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


1.C.98.1.1
The heterotrimeric CDT, CdtA/B/C toxin complex. CdtA and CdtC may form a heterodimeric complex required for CdtB delivery. Localized to the cell outer membrane. Contains a ricin B-type lectin domain (Smith and Bayles 2006).  All three have an N-terminal TMS, and possibly a second one near their C-termini.

Accession Number:Q46668
Protein Name:Cytolethal distending toxin subunit A
Length:258
Molecular Weight:27712.00
Species:Escherichia coli [562]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Cell outer membrane1 / Lipid-anchor2
Substrate molecule

Cross database links:

Pfam: PF03498   

Gene Ontology

GO:0009279 C:cell outer membrane
GO:0005886 C:plasma membrane
GO:0005529 F:sugar binding
GO:0009405 P:pathogenesis

References (1)

[1] “Cloning, sequencing, and expression of the Escherichia coli cytolethal distending toxin genes.”  Pickett C.L.et.al.   8112838

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence 
1:	MANKRTPIFI AGILIPILLN GCSSGKNKAY LDPKVFPPQV EGGPTVPSPD EPGLPLPGPG 
61:	PALPTNGAIP IPEPGTAPAV SLMNMDGSVL TMWSRGAGSS LWAYYIGDSN SFGELRNWQI 
121:	MPGTRPNTIQ FRNVDVGTCM TSFPGFKGGV QLSTAPCKFG PERFDFQPMA TRNGNYQLKS 
181:	LSTGLCIRAN FLGRTPSSPY ATTLTMERCP SSGEKNFEFM WSISEPLRPA LATIAKPEIR 
241:	PFPPQPIEPD EHSTGGEQ